【摘要】：目的了解重慶市渝中區(qū)教師人群高尿酸血癥(HUA)的患病情況,探討血尿酸與血壓水平的關(guān)系。方法對(duì)2010、2012、2014年在重慶市人民醫(yī)院健康管理(體檢)中心進(jìn)行健康體檢的教師8354名體檢報(bào)告結(jié)果進(jìn)行調(diào)查分析。在研究血尿酸水平與血壓的關(guān)系時(shí),納入體檢指標(biāo)完整、未服用藥物的對(duì)象7120名;分析不同尿酸水平人群血壓進(jìn)展情況時(shí),選擇同時(shí)參加2010-2014年健康體檢的同一人群1125人。結(jié)果 2010、2012、2014年重慶市渝中區(qū)教師人群HUA平均檢出率為19.18%(1602/8354),男性HUA檢出率(28.00%)高于女性(15.64%,P0.01)。2014與2010年比較,女性HUA檢出率上升趨勢(shì)明顯,增長(zhǎng)幅度高于男性。將不同性別研究對(duì)象按尿酸四分位水平分組,男性尿酸最高四分位組收縮壓和舒張壓較最低四分位組增加[分別為(134.8±16.8)比(130.0±17.8),(83.4±10.6)比(79.6±9.9)mm Hg],患高血壓的風(fēng)險(xiǎn)增加至2.171倍;女性尿酸最高四分位組收縮壓和舒張壓較最低四分位組增加[分別為(135.1±22.4)比(122.2±17.2),(78.6±10.6)比(74.6±9.3)mm Hg],患高血壓的風(fēng)險(xiǎn)增加至1.351倍(均P0.01)。隨著尿酸水平增高,正常高值血壓者進(jìn)展為高血壓的比例增加(P0.05)。結(jié)論重慶市渝中區(qū)教師人群中HUA的檢出率呈上升趨勢(shì),高尿酸水平與血壓水平相關(guān)。
[Abstract]:Objective to investigate the prevalence of hyperuricemia (Hua) in teachers in Yuzhong District of Chongqing and to explore the relationship between serum uric acid and blood pressure. Methods A total of 8354 teachers who underwent physical examination in the Center of Health Management (physical examination) of Chongqing people's Hospital in 2010 and 2014 were investigated and analyzed. In the study of the relationship between serum uric acid level and blood pressure, 7120 subjects who had not taken drugs were included in the physical examination, and 1125 people who took part in the health check-up from 2010 to 2014 were selected when analyzing the blood pressure progress of people with different uric acid levels. Results the average prevalence rate of Hua in teachers in Yuzhong District of Chongqing in 2014 was 19.18% (1602 / 8354), and that of male (28.00%) was higher than that of female (15.64g / P0.01) .Compared with 2010, the detection rate of HUA in female was higher than that in male. According to the quartile level of uric acid, the systolic and diastolic blood pressure in the highest quartile of uric acid group was higher than that in the lowest quartile group [(134.8 鹵16.8) vs (130.0 鹵17.8), (, 83.4 鹵10.6) vs (79.6 鹵9.9) mm Hg, respectively], and the risk of hypertension was 2.171 times higher than that in the lowest quartile group. Compared with the lowest quartile group, the systolic and diastolic blood pressure in the highest quartile group of uric acid increased [(135.1 鹵22.4) vs (122.2 鹵17.2), (, 78.6 鹵10.6) mm Hg, respectively], and the risk of hypertension increased to 1.351 times (all P0.01). With the increase of uric acid level, the proportion of patients with normal high blood pressure progression to hypertension increased (P0.05). Conclusion the prevalence of UA in teachers in Yuzhong District of Chongqing is on the rise, and the level of high uric acid is related to blood pressure.
【作者單位】： 重慶市人民醫(yī)院健康管理(體檢)中心;
【基金】：重慶市衛(wèi)生局醫(yī)學(xué)科學(xué)技術(shù)研究項(xiàng)目(2010-2-283)
【分類(lèi)號(hào)】：R544.1;R589.7

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