發(fā)布時間：2018-06-30 21:30

  本文選題：生態(tài)免疫營養(yǎng) + 歸脾湯��； 參考：《浙江中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的觀察腸內(nèi)生態(tài)免疫營養(yǎng)支持聯(lián)合中藥歸脾湯加減治療老年營養(yǎng)不良患者的臨床效果,進(jìn)一步闡明氣血兩虛導(dǎo)致老年營養(yǎng)不良的病理實質(zhì),豐富中醫(yī)藥治療虛勞病癥的科學(xué)內(nèi)涵。方法將120例老年營養(yǎng)不良患者作為研究對象,按照隨機(jī)對照原則分為對照組、生態(tài)免疫營養(yǎng)組和中藥組各40例。根據(jù)患者每天能量需要量推算出每日營養(yǎng)液攝入量。對照組給予鼻飼瑞代營養(yǎng)液(500ml/袋,450kcal/500ml);生態(tài)免疫組給予鼻飼瑞能營養(yǎng)液(200ml/瓶,260kcal/200ml),鼻飼復(fù)方嗜酸乳桿菌片,4片/次,3次/天;中藥組給予在生態(tài)免疫營養(yǎng)組治療基礎(chǔ)上給予中藥歸脾湯加減鼻飼治療,中藥濃煎至60ml,每次一劑,2次/天。三組患者均治療2周。治療結(jié)束后分別從臨床療效、一般情況、中醫(yī)癥候量表評分、生化指標(biāo)、免疫學(xué)指標(biāo)等情況進(jìn)行對比分析觀察臨床療效。結(jié)果1.中藥組的小腿圍長度較治療前增加(P=0.025),且其中醫(yī)癥候積分較生態(tài)免疫組、對照組比較下降(P0.05)。2.中藥組的總白蛋白水平較生態(tài)免疫組、對照組明顯提高(P=0.003);血紅蛋白水平較生態(tài)免疫組、對照組明顯提高(P=0.043);中藥組的總膽固醇水平及甘油三酯水平較治療前下降,且高密度脂蛋白水平較前升高(P0.05)。3.中藥組的IgA水平較生態(tài)免疫組、對照組明顯提高(P=0.015)。4.中藥組腸內(nèi)營養(yǎng)并發(fā)癥發(fā)生率較生態(tài)免疫組、對照組降低,包括腹瀉、腹脹等不適。結(jié)論腸內(nèi)生態(tài)免疫營養(yǎng)支持聯(lián)合中藥歸脾湯能改善患者營養(yǎng)狀態(tài),增強(qiáng)機(jī)體免疫功能,且中藥在治療慢性疾病有獨特優(yōu)勢和良好療效,副作用低。
[Abstract]:Objective to observe the clinical effect of enteral ecological immune nutrition support combined with traditional Chinese medicine Guipi decoction in the treatment of senile malnutrition, and to further clarify the pathological essence of senile malnutrition caused by deficiency of qi and blood. Enrich the scientific connotation of TCM treatment of asthenia. Methods 120 patients with senile malnutrition were divided into control group, ecological immune nutrition group and traditional Chinese medicine group according to the principle of random control. Daily nutrient intake was calculated according to the patient's daily energy requirement. The control group was given 500ml/ bag 450kcal / 500ml, the ecological immunization group was given 200ml/ 260kcal / 200ml, and the nasal feeding compound Lactobacillus acidophilus tablets 4 times a day. The traditional Chinese medicine group was given traditional Chinese medicine Guipi decoction to 60 ml twice a day on the basis of ecological immune nutrition group. All the patients in the three groups were treated for 2 weeks. At the end of the treatment, the clinical efficacy was compared and analyzed from clinical effect, general situation, TCM symptom scale score, biochemical index, immunological index and so on. Result 1. The leg circumference length of the traditional Chinese medicine group increased compared with that before treatment (P0. 025), and its TCM symptom score was higher than that of the ecological immune group, while the control group decreased (P0.05). 2. The total albumin level in the Chinese medicine group was significantly higher than that in the ecological immunization group and the control group (P0. 003), the hemoglobin level in the traditional Chinese medicine group was significantly higher than that in the ecological immunization group (P0. 043), the total cholesterol level and triglyceride level in the Chinese medicine group were lower than those before treatment. The level of high density lipoprotein was higher than that before (P0.05). 3. The IgA level in the Chinese medicine group was significantly higher than that in the ecological immunization group and the control group (P0. 015). 4. 4. The incidence of enteral nutrition complications in the Chinese medicine group was lower than that in the ecological immunization group and the control group, including diarrhea, abdominal distension and other discomfort. Conclusion Eco-immune nutrition support combined with Guipi decoction can improve the nutritional status of the patients and enhance the immune function of the patients. The traditional Chinese medicine has unique advantages and good efficacy in the treatment of chronic diseases with low side effects.
【學(xué)位授予單位】：浙江中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R591

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 張飛燕;李晶晶;周瑩;徐曉玉;;安神類中藥及其有效成分對神經(jīng)遞質(zhì)鎮(zhèn)靜催眠機(jī)制的研究進(jìn)展[J];中國中藥雜志;2016年23期

2 高月穎;;黃芪的藥理作用及臨床應(yīng)用分析[J];中國醫(yī)藥指南;2016年28期

3 向韻;孟盼;張秀麗;雷昌;黃丹;蔡川;蔡光先;王宇紅;;甘麥大棗湯促進(jìn)中樞興奮性藥理作用研究[J];亞太傳統(tǒng)醫(yī)藥;2016年18期

4 李海聰;楊毅玲;李求兵;王燕;楊學(xué)青;田心;陳曉光;王博元;;歸脾湯加減中藥治療老年高血壓病合并抑郁癥及對患者血壓和生活質(zhì)量的影響[J];中華中醫(yī)藥雜志;2016年08期

5 王立偉;王鍵瑋;魏秀芹;賈軍鋒;強(qiáng)薇;賈偉;;腸內(nèi)免疫營養(yǎng)聯(lián)合微生態(tài)制劑對進(jìn)展期胃癌術(shù)后輔助化療的臨床作用研究[J];中國實用內(nèi)科雜志;2016年07期

6 姬芳勤;;合并營養(yǎng)不良的胃腸道惡性腫瘤患者術(shù)后應(yīng)用腸內(nèi)免疫營養(yǎng)的臨床研究[J];臨床醫(yī)藥文獻(xiàn)電子雜志;2016年17期

7 趙雨坤;李立;劉學(xué);程仕萍;郭晴晴;樊丹平;鄭康;何小鵑;呂愛平;;基于系統(tǒng)藥理學(xué)探索甘草有效成分甘草甜素的藥理作用機(jī)制[J];中國中藥雜志;2016年10期

8 岳美穎;潘媛;敖慧;;白術(shù)化學(xué)、藥理與臨床研究進(jìn)展[J];亞太傳統(tǒng)醫(yī)藥;2016年05期

9 倪永華;周艷;;歸脾湯加減輔以西藥治療氣虛不攝型消化型潰瘍伴出血臨床觀察[J];中華中醫(yī)藥學(xué)刊;2016年02期

10 楊燕青;何昱君;沈潔;謝志軍;;基于腸道菌群與免疫失調(diào)相關(guān)性探討從脾論治白塞綜合征[J];安徽中醫(yī)藥大學(xué)學(xué)報;2016年01期

，

本文編號：2086916