本文選題：心率 + 糖化血紅蛋白　； 參考：《臨床心血管病雜志》2017年01期

【摘要】：目的:分析2型糖尿病患者的靜息心率和與年齡、糖尿病病程、糖化血紅蛋白(HbA1c)、空腹血糖(FPG)、餐后2h血糖(2hPG)、體質(zhì)指數(shù)(BMI)的相關(guān)性,及伴高血壓、冠心病患者的心率現(xiàn)狀和危險(xiǎn)因素,為降低心性猝死發(fā)病率提供理論依據(jù)。方法:采用橫斷面調(diào)查方法對(duì)2014-04-2016-03我院住院的2型糖尿病患者按順序入組,進(jìn)行病案檢索,記錄一般情況和心率、糖尿病病程、HbA1c、FPG、2hPG、BMI、合并癥及用藥情況。共調(diào)查2 012例患者,進(jìn)入分析的2型糖尿病患者1 566例。其中單純2型糖尿病患者830例,2型糖尿病合并高血壓患者588例,2型糖尿病合并冠心病患者46例,2型糖尿病合并高血壓和冠心病患者102例,有影響心率因素(起搏器植入、發(fā)熱、甲亢、應(yīng)用β受體阻滯劑和非二氫吡啶類(lèi)鈣拮抗劑)、影響血紅蛋白因素(貧血、脾亢)、嚴(yán)重肝腎損害疾病患者341例和溯源問(wèn)題105例均未納入分析。心率的測(cè)量用12導(dǎo)聯(lián)心電圖機(jī)以臥位靜息為準(zhǔn);HbA1c、FPG、2hPG以空腹靜脈血為準(zhǔn),采用葡萄糖氧化酶法,進(jìn)行生化儀檢測(cè);BMI的采集用體重身高測(cè)量?jī)x測(cè)量身高、體重,用BMI=體重(kg)/身高(cm)~2公式求得。結(jié)果:2型糖尿病住院患者的靜息平均心率為76.24次/min,主要分布區(qū)間在70~79次/min,在單純2型糖尿病患者中心率≥80次/min者占37.47%,≥90次/min者占14.82%。雙變量相關(guān)分析顯示年齡與心率呈負(fù)相關(guān)(r=-0.098,P=0.005),HbA1c、FPG和2hPG分別與心率呈正相關(guān)(分別為r=0.170,P=0.000;r=0.148,P=0.000;r=0.199,P=0.000),而與糖尿病病程和BMI不相關(guān)。HbA1c、FPG、2hPG控制欠佳者心率顯著增快。2型糖尿病患者、2型糖尿病伴高血壓患者、伴冠心病患者、伴高血壓和冠心病患者的靜息平均心率分別為(76.42±11.86)、(76.58±11.42)、(77.37±11.08)及(72.28±11.50)次/min。糖尿病合并高血壓風(fēng)險(xiǎn)增加與年齡、BMI有關(guān),合并冠心病風(fēng)險(xiǎn)增加與糖尿病病程有關(guān)。結(jié)論:2型糖尿病患者心率偏快,與長(zhǎng)期血糖控制不理想致糖尿病心肌損害有關(guān)。因此,HbA1c達(dá)標(biāo)對(duì)防治糖尿病心肌損害具有重要意義。
[Abstract]:Objective: to analyze the relationship between resting heart rate and age, diabetes course, HbA1c, FPG, 2 h postprandial blood glucose (2hPG), body mass index (BMI) and hypertension in type 2 diabetic patients. The present situation and risk factors of heart rate in patients with coronary heart disease provide theoretical basis for reducing the incidence of sudden cardiac death. Methods: the patients with type 2 diabetes mellitus hospitalized in our hospital from 2014-04-2016-03 were selected by cross-sectional investigation. The medical records were searched, the general situation and heart rate were recorded, the course of diabetes mellitus (HbA1cFPGN) 2hPGN BMIs, complications and drug use were recorded. A total of 2 012 patients were investigated and 1 566 patients with type 2 diabetes were enrolled in the analysis. Among them, there were 830 patients with type 2 diabetes mellitus complicated with hypertension, 588 patients with type 2 diabetes mellitus complicated with coronary heart disease, 46 patients with type 2 diabetes mellitus complicated with hypertension and 102 patients with coronary heart disease. Hyperthyroidism, 尾 -receptor blockers and non-dihydropyridine calcium antagonists), hemoglobin factors (anemia, hypersplenism), serious liver and kidney damage in 341 patients and traceability in 105 cases were not included in the analysis. The heart rate was measured by 12-lead electrocardiograph in the resting position of HbA1cFPGG 2hPG, the fasting venous blood was measured by glucose oxidase method, and the body height and weight were measured by weight height meter. BMI = weight (kg) / height (cm) 2 formula was used. Results the average resting heart rate of the hospitalized patients with type 2 diabetes mellitus was 76.24 beats / min, the main distribution was 70 ~ 79 times / min, and the center rate 鈮，

本文編號(hào)：2067751