薯蕷粥對老年2型糖尿病患者血清SOD、GSH-Px的影響
發(fā)布時間:2018-06-23 12:00
本文選題:薯蕷粥 + 型糖尿病。 參考:《中國老年學(xué)雜志》2017年13期
【摘要】:目的探討薯蕷粥對老年2型糖尿病(T2DM)患者血清超氧化物歧化酶(SOD)、谷胱甘肽過氧化物酶(GSH-Px)、丙二醛(MDA)等的影響。方法老年T2DM患者90例用隨機(jī)數(shù)字表法分為試驗組和對照組各45例。對照組進(jìn)行門診隨訪和糖尿病俱樂部健康教育,試驗組在此基礎(chǔ)上施予薯蕷粥,1次/d,連續(xù)干預(yù)12w。干預(yù)前后檢測各組的觀測指標(biāo),采用符合方案分析(PP)和意向性分析(ITT)對兩組數(shù)據(jù)進(jìn)行統(tǒng)計分析。結(jié)果PP和ITT顯示,兩組SOD、GSH-Px、活性氧自由基(AOR)、空腹血糖(FPG)和餐后2h血糖(2hPG)水平差異有統(tǒng)計學(xué)意義(P0.05),兩組血清MDA水平無統(tǒng)計學(xué)意義(P0.05)。結(jié)論薯蕷粥初步顯示出對老年T2DM患者SOD、GSH-Px、AOR的調(diào)節(jié)作用,對降低FPG和2hPG的作用也得到初步驗證,對MDA的影響不確定。
[Abstract]:Objective to investigate the effects of Dioscorea zingiberensis on serum superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and malondialdehyde (MDA) in elderly patients with type 2 diabetes mellitus (T2DM). Methods 90 elderly patients with T2DM were randomly divided into two groups: experimental group (n = 45) and control group (n = 45). The control group was followed up and diabetes club health education was carried out. On this basis, the experimental group was given Dioscorea zingiberensis once a day for 12 weeks. The observation indexes of each group were measured before and after intervention, and the two groups of data were statistically analyzed by coincidence analysis (PP) and intentionality analysis (ITT). Results PP and ITT showed that the levels of GSH-Px, active oxygen free radical (AOR), fasting blood glucose (FPG) and 2 h postprandial blood glucose (2hPG) in the two groups were significantly different (P0.05), but no significant difference was found in the serum MDA levels between the two groups (P0.05). Conclusion Dioscorea zingiberensis preliminarily showed the regulating effect on SODH-PxAOR in elderly patients with T2DM. The effect of dioscorea zingiberensis on the decrease of FPG and 2hPG was also preliminarily verified, and the effect on MDA was uncertain.
【作者單位】: 福建中醫(yī)藥大學(xué);福建省立醫(yī)院;
【基金】:國家自然科學(xué)基金(81503438) 2014年福建中醫(yī)藥大學(xué)重點學(xué)科專項校管課題(X2014064-學(xué)科)
【分類號】:R587.1
【共引文獻(xiàn)】
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1 楊雄;;高中化學(xué)實驗出現(xiàn)異,F(xiàn)象的原因及積極意義[J];中學(xué)教學(xué)參考;2017年14期
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