類風(fēng)濕關(guān)節(jié)炎達(dá)標(biāo)治療相關(guān)影響因素的臨床研究
發(fā)布時間:2018-06-21 16:33
本文選題:關(guān)節(jié)炎 + 類風(fēng)濕; 參考:《中華疾病控制雜志》2016年06期
【摘要】:目的調(diào)查類風(fēng)濕關(guān)節(jié)炎患者(rheumatoid arthritis,RA)達(dá)標(biāo)治療情況,分析其影響因素,進(jìn)一步提高RA達(dá)標(biāo)治療率。方法選擇300例RA患者,詳細(xì)記錄所有患者臨床資料,并根據(jù)28關(guān)節(jié)疾病活動性(disease activity score in 28 joints,DAS28)評分分為達(dá)標(biāo)組和未達(dá)標(biāo)組。結(jié)果 RA患者中,達(dá)標(biāo)率為36.7%;達(dá)標(biāo)組和未達(dá)標(biāo)組比較:達(dá)標(biāo)組比未達(dá)標(biāo)組患者平均年齡輕、文化程度高、關(guān)節(jié)腫脹數(shù)/關(guān)節(jié)壓痛數(shù)少、疼痛程度評分/患者總體評估/醫(yī)師總體評估(physician global assessment,PGA)低;達(dá)標(biāo)組持續(xù)使用致病情緩解抗風(fēng)濕病藥(disease-modifying anti-rheumatic drugs,DMARDs)單藥或聯(lián)合治療時間≥3個月所占比例高于未達(dá)標(biāo)組;達(dá)標(biāo)患者類風(fēng)濕因子、紅細(xì)胞沉降率、C反應(yīng)蛋白、關(guān)節(jié)功能分級、生活質(zhì)量得分低于未達(dá)標(biāo)患者;Logistic回歸分析顯示:關(guān)節(jié)功能分級、C反應(yīng)蛋白、PGA是RA達(dá)標(biāo)治療獨立影響因素。結(jié)論 RA患者達(dá)標(biāo)治療率仍較低,DMARDs正規(guī)治療對達(dá)標(biāo)治療具有重要作用,關(guān)節(jié)功能、C反應(yīng)蛋白、PGA為RA達(dá)標(biāo)治療獨立影響因素。
[Abstract]:Objective to investigate the treatment of rheumatoid arthritis (RA) in rheumatoid arthritis (RA) and analyze its influencing factors. Methods three hundred patients with RA were selected and all the clinical data were recorded in detail. According to the score of 28 joint disease activity score in 28 join as 28, the patients were divided into two groups: the control group and the non-standard group. Results in RA patients, the rate of reaching the standard was 36.7%, the average age of the patients in the standard group was lower than that in the non-standard group, the education level was higher, the number of joint swelling / joint tenderness was less than that in the non-standard group. The scores of pain degree / total assessment of patients / physicians' overall assessment of PGAs were lower, the proportion of patients with persistent use of disease mitigation drug DMARDs1 or DMARDs鈮,
本文編號:2049496
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