本文選題：25羥維生素D/25(0H)D + 維生素D缺乏　； 參考：《寧夏醫(yī)科大學》2017年碩士論文

【摘要】：目的:調(diào)查目前甘肅省健康成人的維生素D水平狀況,并分析維生素D缺乏的危險因素,評價其與代謝性相關因素的關系,為防治維生素D缺乏提供流行病學依據(jù)。方法:采用整群分層隨機的抽樣調(diào)查方法,于2014年6月至2015年11月,在甘肅省7個地區(qū)抽取18-79歲5年以上的常住居民11 300人,并對其進行問卷調(diào)查、物理測量、生化檢查和骨密度檢測。并對數(shù)據(jù)資料進行統(tǒng)計學分析。結(jié)果:1.共有11 157名(男性4 740名,女性6 417名)調(diào)查對象完成該項研究。2.總?cè)巳旱难?5(0H)D平均水平為13.8(11.0,17.8)ng/m L。3.維生素D嚴重缺乏(10ng/m L)、缺乏(10-20ng/m L)、不足(20-30ng/m L)、正常(≥30 ng/m L)現(xiàn)患率分別為17.3%,64.6%,11.8%和6.3%。4.維生素D缺乏的獨立危險因素包括年齡、性別,而日照、運動和鈣劑的補充為保護性因素(P0.05)。5.血清25(OH)D的水平與血清甲狀旁腺激素呈負相關(r=-0.279,P0.001),與血鈣(r=0.239,P0.01),血磷(r=0.090,P=0.018),血清低密度脂蛋白(r=0.100,P=0.008)和BMI(r=0.093,P=0.014)呈正相關。在所有受試者中,血清25(OH)D的水平與BMD無統(tǒng)計學差異(P0.05)。結(jié)論:維生素D缺乏普遍存在于甘肅地區(qū)成年人群,尤其多見于女性和較年輕者,并受日照、活動、鈣劑等因素影響,需要采取積極的綜合措施進行干預。
[Abstract]:Objective: to investigate the status of vitamin D levels in healthy adults in Gansu Province at present, analyze the risk factors of vitamin D deficiency, evaluate the relationship between vitamin D deficiency and metabolic factors, and provide epidemiological basis for the prevention and treatment of vitamin D deficiency. Methods: from June 2014 to November 2015, 11 300 permanent residents aged 18 to 79 years were selected from 7 districts of Gansu Province by cluster stratified random sampling, and were investigated by questionnaire and physical measurement. Biochemical examination and bone mineral density test. The data were analyzed statistically. The result is 1: 1. A total of 11,157 subjects (4,740 males and 6,417 females) completed the study. The average serum concentration of 25g / mg / ml 路L ~ (-1) D in the total population was 13.8ng / mL ~ (-1) and 17.8ng / mL ~ (-1) 路m ~ (-1). Vitamin D was severely deficient in 10 ng / m L ~ (-1), 10 ~ (-20) ng / m ~ (-1) L ~ (-1), 20 ~ (30) ng / m ~ (-1) L ~ (-1). The prevalence rates of normal (鈮，

本文編號：2001696