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有氧運(yùn)動(dòng)和抗阻運(yùn)動(dòng)對(duì)糖調(diào)節(jié)受損患者空腹血糖及胰島素抵抗的影響研究

發(fā)布時(shí)間:2018-06-08 16:38

  本文選題:糖尿病前期 + 有氧運(yùn)動(dòng) ; 參考:《中國(guó)全科醫(yī)學(xué)》2017年29期


【摘要】:目的探討有氧運(yùn)動(dòng)和抗阻運(yùn)動(dòng)對(duì)糖調(diào)節(jié)受損(IGR)患者空腹血糖(FPG)和胰島素抵抗的干預(yù)效果,為有效預(yù)防和延緩糖尿病前期進(jìn)展為糖尿病提供依據(jù)。方法于2015年6—8月在桂林市疊彩、南門(mén)及秀峰社區(qū)衛(wèi)生服務(wù)中心長(zhǎng)期管理的居民中篩選IGR患者143例,采用隨機(jī)數(shù)字表法分為對(duì)照組(47例)、有氧組(48例)、抗阻組(48例)。對(duì)照組每3個(gè)月隨訪(fǎng)1次,但不對(duì)其進(jìn)行行為干預(yù)。有氧組進(jìn)行中等強(qiáng)度的有氧運(yùn)動(dòng),主要為韻律操、有氧健身操等?棺杞M進(jìn)行中等強(qiáng)度的抗阻運(yùn)動(dòng),采用彈力繩以60%~70%的單次最大負(fù)荷完成指定動(dòng)作,主要選取腰背部及腹部肌群、腿部及臀部肌群、上肢肌群進(jìn)行訓(xùn)練。有氧組和抗阻組總運(yùn)動(dòng)時(shí)間均為50 min/次,隔日1次。分別于干預(yù)前及干預(yù)3、6、12個(gè)月時(shí)檢測(cè)FPG、空腹胰島素(FINS)水平,計(jì)算胰島素抵抗指數(shù)(HOMA-IR)、胰島素作用指數(shù)(IAI)。結(jié)果干預(yù)結(jié)束后,對(duì)照組38例、有氧組39例、抗阻組38例完成本研究。時(shí)間與運(yùn)動(dòng)方式對(duì)FPG、FINS、HOMA-IR、IAI的交互作用顯著,時(shí)間、運(yùn)動(dòng)方式對(duì)FPG、FINS、HOMA-IR、IAI的主效應(yīng)顯著(P0.05)。干預(yù)3個(gè)月時(shí),有氧組、抗阻組FPG低于對(duì)照組;干預(yù)6個(gè)月時(shí),有氧組、抗阻組FPG、FINS、HOMA-IR低于對(duì)照組,IAI高于對(duì)照組,抗阻組FPG低于有氧組;干預(yù)12個(gè)月時(shí),有氧組、抗阻組FPG、FINS、HOMA-IR低于對(duì)照組,IAI高于對(duì)照組(P0.05)。干預(yù)3個(gè)月時(shí),有氧組、抗阻組FPG、HOMA-IR低于干預(yù)前,IAI高于干預(yù)前;干預(yù)6個(gè)月時(shí),有氧組、抗阻組FPG、FINS、HOMA-IR低于干預(yù)前,IAI高于干預(yù)前;干預(yù)12個(gè)月時(shí),有氧組、抗阻組FPG低于干預(yù)前,對(duì)照組、有氧組、抗阻組FINS、HOMA-IR低于干預(yù)前,IAI高于干預(yù)前(P0.05)。結(jié)論有氧運(yùn)動(dòng)和抗阻運(yùn)動(dòng)對(duì)IGR患者的FPG、FINS、胰島素抵抗、胰島素敏感性均有明顯的改善作用,效果相似。
[Abstract]:Objective to investigate the effects of aerobic exercise and resistance exercise on fasting blood glucose (FPG) and insulin resistance in patients with impaired glucose regulation (IGR), so as to provide evidence for preventing and delaying the advance of diabetes mellitus. Methods 143 IGR patients were selected from the residents in Guilin City from June to August 2015. The IGR patients were randomly divided into control group (n = 47), aerobic group (n = 48) and resistance group (n = 48). The control group was followed-up once every 3 months, but did not intervene in their behavior. The aerobic group carries on the moderate intensity aerobic exercise, mainly for the rhythm exercise, the aerobic aerobics and so on. In the resistance group, the middle strength resistance exercise was carried out, and the designated action was completed by using elastic rope with a single maximum load of 60% and 70%, mainly selecting the waist, back and abdomen muscles, the leg and hip muscles, and the upper limb muscle group for training. The total exercise time of aerobic group and resistance group was 50 min/ once every other day. The levels of FPG, fasting insulin and fins were measured before intervention and at 6 and 12 months after intervention respectively. The insulin resistance index (HOMA-IRN) and insulin action index (IIA) were calculated. Results after the intervention, 38 cases in the control group, 39 cases in the aerobic group and 38 cases in the resistance group completed the study. The interaction between time and exercise mode on FPGN FINSH-IRMA-IRIAI was significant, and time and exercise mode had significant effect on FPGG FINSH-IRMA-IRI IAI (P0.05). At 3 months of intervention, FPG in the aerobic group was lower than that in the control group, and at 6 months after intervention, the FPG of the aerobic group was lower than that of the control group, and the FPG of the resistance group was lower than that of the aerobic group. At 12 months after intervention, the FPG in the aerobic group was lower than that in the control group, and at 12 months after intervention, the FPG of the resistance group was lower than that of the aerobic group. HOMA-IR in resistance group was lower than that in control group (P 0.05). In aerobic group, HOMA-IR of resistance group was lower than that before intervention, and at 6 months after intervention, the level of FINSHOMA-IR in aerobic group was lower than that before intervention. At 12 months after intervention, FPG in aerobic group was lower than that before intervention. FINSHOMA-IR in control group, aerobic group and resistance group was lower than that before intervention (P 0.05). Conclusion aerobic exercise and resistance exercise can significantly improve FPGG FINS, insulin resistance and insulin sensitivity in IGR patients, and the effects are similar.
【作者單位】: 廣西醫(yī)科大學(xué)第一附屬醫(yī)院內(nèi)科;廣西中醫(yī)藥大學(xué)第一附屬醫(yī)院護(hù)理部;廣西醫(yī)科大學(xué)護(hù)理學(xué)院科教科;
【基金】:廣西醫(yī)療衛(wèi)生適宜技術(shù)研究與開(kāi)發(fā)課題項(xiàng)目(S201413-03) 廣西研究生教育創(chuàng)新計(jì)劃項(xiàng)目(YCSZ2015111)
【分類(lèi)號(hào)】:R587.1

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