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2型糖尿病患者腹脹與小腸細(xì)菌過度生長(zhǎng)的關(guān)系

發(fā)布時(shí)間:2018-05-31 13:45

  本文選題:型糖尿病 + 小腸細(xì)菌過度生長(zhǎng) ; 參考:《山東大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2016年01期


【摘要】:目的探討2型糖尿病患者腹脹與小腸細(xì)菌過度生長(zhǎng)(SIBO)的關(guān)系。方法將96例2型糖尿病患者分為血糖正常且無(wú)腹脹組、血糖正常并腹脹組、血糖升高無(wú)腹脹組、血糖升高并腹脹4組,通過乳果糖氫呼氣試驗(yàn)分別檢測(cè)其SIBO情況及口盲時(shí)間,并與健康對(duì)照組進(jìn)行組間比較分析。結(jié)果血糖升高并腹脹組患者的SIBO陽(yáng)性率較其他組患者明顯增高,差異有統(tǒng)計(jì)學(xué)意義。腹脹組SIBO陽(yáng)性率與健康對(duì)照組比較有統(tǒng)計(jì)學(xué)差異(P0.05),4組患者口盲時(shí)間與健康對(duì)照組比較均有統(tǒng)計(jì)學(xué)意義(P0.01)。結(jié)論 2型糖尿病合并腹脹患者易發(fā)生SIBO,與口盲時(shí)間延長(zhǎng)相關(guān),其可能是腹脹發(fā)生的重要發(fā)病機(jī)制。
[Abstract]:Objective to investigate the relationship between abdominal distension and intestinal bacterial overgrowth in type 2 diabetes mellitus. Methods 96 patients with type 2 diabetes mellitus were divided into 4 groups: normal blood glucose and no abdominal distension group, normal blood glucose with abdominal distention group, no abdominal distention group with elevated blood glucose, and 4 groups with elevated blood glucose and abdominal distention. The SIBO and oral blindness time were measured by hydrogen breath test of lactulose. And compared with the healthy control group. Results the positive rate of SIBO in patients with hyperglycemia and abdominal distension was significantly higher than that in other groups. The positive rate of SIBO in the abdominal distension group was significantly higher than that in the healthy control group (P 0.05) and the time of oral blindness in the 4 groups was significantly higher than that in the healthy control group (P 0.01). Conclusion SIBO is easy to occur in type 2 diabetes mellitus patients with abdominal distension, which may be an important pathogenesis of abdominal distension.
【作者單位】: 東莞東華醫(yī)院消化內(nèi)科;河南大學(xué)護(hù)理學(xué)院;
【分類號(hào)】:R587.1
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本文編號(hào):1959948

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