發(fā)布時(shí)間：2018-05-30 17:06

  本文選題：糖尿病酮癥酸中毒 + GCS評(píng)分　； 參考：《第三軍醫(yī)大學(xué)學(xué)報(bào)》2017年16期

【摘要】：目的回顧性分析糖尿病酮癥酸中毒(diabetic ketoacidosis,DKA)患者預(yù)后相關(guān)因素,以期提高DKA診治水平及降低病死率。方法收集本院內(nèi)分泌科2014年1月至2016年12月收治的DKA住院患者臨床資料。根據(jù)DKA患者是否存活分為存活組和死亡組,并回顧性分析2組患者基本情況、入院時(shí)血常規(guī)、肝腎功、電解質(zhì)、C反應(yīng)蛋白、格拉斯哥昏迷評(píng)分(Glasgow coma scale,GCS)、急性生理與慢性健康評(píng)分Ⅱ(acute physiology and chronic health evaluation scoreⅡ,APACHEⅡ)等觀察指標(biāo)及預(yù)后情況。結(jié)果共納入患者70例,其中男性36例,女性34例,年齡(42.63±15.67)歲。經(jīng)統(tǒng)計(jì)分析結(jié)果顯示,存活組患者GCS評(píng)分[(14.41±1.42)vs(11.36±3.14)]、血磷[(0.96±0.47)mg/L vs(0.68±0.60)mg/L]明顯高于死亡組(P0.05,P0.01),存活組APACHEⅡ評(píng)分[(8.58±4.63)vs(15.73±4.38)]、白細(xì)胞總數(shù)[(14.82±9.55)×10~9/L vs(22.80±7.67)×10~9/L]、C反應(yīng)蛋白[(33.67±45.70)mg/L vs(211.39±173.93)mg/L]、肌酐[(87.28±43.89)μmol/L vs(136.47±87.50)μmol/L]、尿素氮[(8.45±5.00)mmol/L vs(14.72±9.23)mmol/L]明顯低于死亡組(P0.05,P0.01)。DKA患者GCS評(píng)分(OR=0.510,P0.05)越低、APACHEⅡ評(píng)分(OR=1.300,P0.05)及C反應(yīng)蛋白(OR=1.031,P0.05)越高,預(yù)后則越差。結(jié)論 C反應(yīng)蛋白、GCS評(píng)分、APACHEⅡ評(píng)分是DKA患者獨(dú)立的預(yù)后因素。
[Abstract]:Objective to retrospectively analyze the prognostic factors of diabetic ketoacidosis (DKA) patients with diabetic ketoacidosis in order to improve the diagnosis and treatment of diabetic ketoacidosis and reduce the mortality. Methods the clinical data of DKA patients admitted to our hospital from January 2014 to December 2016 were collected. Patients with DKA were divided into survival group and death group according to their survival. The basic condition, blood routine, liver and kidney function, electrolytes C-reactive protein were analyzed retrospectively. Glasgow coma scale, acute physiology and chronic health 鈪，

本文編號(hào)：1956064