本文選題：冠狀動(dòng)脈疾病 + 高血壓��； 參考：《山東醫(yī)藥》2017年01期

【摘要】：目的觀察冠心病、高血壓及其合并糖尿病狀態(tài)下肥胖程度的差異,探討不同肥胖指標(biāo)對(duì)其患病風(fēng)險(xiǎn)的評(píng)估作用。方法選取冠心病、高血壓、糖尿病及無(wú)上述疾病的患者共643例,根據(jù)具體疾病種類將其分為冠心病組120例,高血壓組127例,冠心病合并高血壓組108例,冠心病和(或)高血壓合并糖尿病組164例,無(wú)上述疾病組124例。采用方差分析比較五組肥胖指標(biāo)體質(zhì)量指數(shù)(BMI)、腹圍(WC)、腰身指數(shù)(WHtR)差異,采用二分類Logistics回歸分析肥胖指標(biāo)對(duì)發(fā)病風(fēng)險(xiǎn)的評(píng)估作用,采用受試者工作特征(ROC)曲線分析肥胖指標(biāo)對(duì)疾病的診斷效力。結(jié)果五組間BMI、WC和WHtR比較,差異有統(tǒng)計(jì)學(xué)意義(P均0.05)。Logistics回歸分析顯示BMI、WC和WHtR是高血壓和冠心病合并高血壓發(fā)生的獨(dú)立危險(xiǎn)因素;WC是冠心病和(或)高血壓合并糖尿病發(fā)生的獨(dú)立危險(xiǎn)因素。ROC曲線分析顯示單獨(dú)應(yīng)用肥胖指標(biāo)對(duì)疾病的診斷效力較弱,聯(lián)合心血管代謝因素可以使診斷效力提高。結(jié)論冠心病、高血壓和(或)糖尿病患者不同肥胖指標(biāo)存在差異,檢測(cè)不同肥胖指標(biāo)可用于上述疾病的初步篩查。
[Abstract]:Objective to observe the difference of obesity in coronary heart disease (CHD), hypertension and diabetes mellitus (DM). Methods A total of 643 patients with coronary heart disease, hypertension, diabetes mellitus and no such diseases were selected and divided into coronary heart disease group (n = 120), hypertension group (n = 127) and coronary heart disease complicated with hypertension group (n = 108). 164 cases of coronary heart disease and / or hypertension with diabetes mellitus, 124 cases of no above disease group. The body mass index (BMI), abdominal circumference (WCC) and waist mass index (WHTR) of the five obesity indexes were compared by ANOVA. The two classification Logistics regression analysis was used to evaluate the risk of obesity. The effectiveness of obesity index in diagnosis of disease was analyzed by using ROC curve. Results BMI-WC and WHtR were compared among the five groups. 0.05).Logistics regression analysis showed that BMI-WC and WHtR were independent risk factors of hypertension and coronary heart disease complicated with hypertension. WC was the independent risk factor of coronary heart disease and / or hypertension with diabetes mellitus. Linear analysis showed that the diagnosis effect of obesity index alone was weak. Combined cardiovascular metabolic factors can improve diagnostic effectiveness. Conclusion there are differences in different obesity indexes among patients with coronary heart disease, hypertension and / or diabetes, and the detection of different obesity indicators can be used in the preliminary screening of these diseases.
【作者單位】： 南方醫(yī)科大學(xué);廣州軍區(qū)廣州總醫(yī)院;
【基金】：廣東省科技計(jì)劃項(xiàng)目(2013A022100036,2014A020212257)
【分類號(hào)】：R541.4;R544.1;R587.1

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