本文選題：低鈉血癥 + 骨鈉�。� 參考：《山西醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:研究低鈉血癥治療量的鈉在細(xì)胞外液和骨中的分布特征。方法:搜集2011年12月至2016年12月就診于山西醫(yī)科大學(xué)第二醫(yī)院的低鈉血癥患者,制定納入標(biāo)準(zhǔn)和排除標(biāo)準(zhǔn),擬入選30-50例。公式計(jì)算細(xì)胞外液新增的鈉和轉(zhuǎn)移到骨中新增的鈉,對(duì)新增細(xì)胞外液鈉和骨鈉數(shù)據(jù)進(jìn)行正態(tài)分布檢驗(yàn),以及均數(shù)和中位數(shù)計(jì)算,并對(duì)細(xì)胞外液的鈉和轉(zhuǎn)移到骨中的鈉兩組數(shù)據(jù)做t檢驗(yàn)、直線回歸和相關(guān)分析。結(jié)果:最終入組病例30例。細(xì)胞外液新增的鈉離子(X)正態(tài)分析偏度為-0.612和峰度為-0.222,Shapiro-Wilk檢驗(yàn)p0.05,不服從正態(tài)分布。骨中新增鈉離子(Y)正態(tài)分析偏度為-0.146,峰度為-1.479,Shapiro-Wilk檢驗(yàn)p0.05,不服從正態(tài)分布。X-Y差值的正態(tài)分析偏度為0.846,峰度為0.459,Shapiro-Wilk檢驗(yàn)統(tǒng)計(jì)量為0.944,p=0.117(p0.05),服從正態(tài)分布。依據(jù)直線回歸分析結(jié)果可以寫(xiě)出Y=43.5+0.17X;對(duì)自變量(X)與應(yīng)變量(Y)數(shù)據(jù)進(jìn)行回歸系數(shù)t檢驗(yàn)分析,其結(jié)果示p值0.05,無(wú)顯著統(tǒng)計(jì)學(xué)意義。結(jié)論:1.細(xì)胞外液新增的鈉離子和骨中新增鈉離子的數(shù)據(jù)是否正態(tài)分布尚不能證實(shí),其中位數(shù)分別為105.43和64.79,四分之一間距分別為72.24和27.28。2.細(xì)胞外液新增的鈉離子毫摩爾數(shù)顯著高于骨中新增鈉離子。3.應(yīng)變量(Y)=43.5+0.17自變量(X)直線回歸關(guān)系尚不能成立。
[Abstract]:Objective: to study the distribution of sodium in extracellular fluid and bone of hyponatremia. Methods: patients with hyponatremia who were admitted to the second Hospital of Shanxi Medical University from December 2011 to December 2016 were collected and included in the study. The formula calculates the additional sodium in extracellular fluid and the new sodium transferred to bone. The data of new extracellular fluid sodium and bone sodium are tested for normal distribution, and the mean and median are calculated. T test, linear regression and correlation analysis were performed for sodium in extracellular fluid and sodium transferred to bone. Results: there were 30 cases in the final group. The normal analytical bias and kurtosis of the new sodium ion X in extracellular fluid were -0.612 and -0.222% Shapiro-Wilk test, respectively. The normal analysis bias of the newly added sodium ion Y) in bone was -0.146, the kurtosis was -1.479% Shapiro-Wilk test (p 0.05), the normal analysis bias of the normal distribution. X-Y difference value was 0.846, the kurtosis was 0.459m Shapiro-Wilk test statistics was 0.944%, and the normal distribution was obtained. According to the results of linear regression analysis, we can write out the data of Yeng 43.5 0.17X.The regression coefficient t test analysis of the data of independent variable X) and strain variable Y) shows that the value of p is 0.05, which has no significant statistical significance. Conclusion 1. The normal distribution of the new sodium ions in extracellular fluid and bone was not confirmed. The median values were 105.43 and 64.79, and the spacing of 1/4 were 72.24 and 27.28.2respectively. The number of new sodium ions in extracellular fluid was significantly higher than that in bone. The linear regression relationship between the dependent variable and the independent variable is 43.5. 0. 17 and cannot be established.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R591.1

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