本文選題：糖尿病 + 急性闌尾炎��； 參考：《中華醫(yī)院感染學(xué)雜志》2017年12期

【摘要】：目的調(diào)查糖尿病并發(fā)急性闌尾炎術(shù)后切口感染的病原菌及其耐藥性特點,并對危險因素進行分析。方法回顧性分析2014年3月-2016年3月期間醫(yī)院收治的159例糖尿病并發(fā)急性闌尾炎患者的細菌培養(yǎng)、藥敏試驗結(jié)果和臨床資料情況。結(jié)果 159例糖尿病并發(fā)急性闌尾炎患者發(fā)生切口感染38例,感染率為23.90%;共分離得到46株病原菌,其中革蘭陰性菌29株(63.04%),革蘭陽性菌17株(36.96%);大腸埃希菌、銅綠假單胞菌及金黃色葡萄球菌均對氨芐西林、哌拉西林的耐藥率較高(均70.00%);χ~2檢驗分析,糖尿病并發(fā)急性闌尾炎術(shù)后切口感染與年齡、闌尾炎類型、住院時間、術(shù)前血糖、術(shù)后血糖和手術(shù)時間呈顯著相關(guān)性(P0.05);Logistic回歸模型分析顯示,年齡、闌尾炎類型、術(shù)后血糖和手術(shù)時間是糖尿病并發(fā)急性闌尾炎術(shù)后切口感染的獨立危險因素(P0.05)。結(jié)論糖尿病并發(fā)急性闌尾炎術(shù)后切口感染以革蘭陰性菌為主,耐藥現(xiàn)象較為嚴(yán)重,危險因素較多,臨床應(yīng)根據(jù)藥敏試驗結(jié)果和相關(guān)因素采取針對性預(yù)防控制措施。
[Abstract]:Objective to investigate the pathogenic bacteria and drug resistance of incision infection in diabetes mellitus complicated with acute appendicitis, and to analyze the risk factors. Methods the bacterial culture, drug sensitivity test and clinical data of 159 patients with diabetes mellitus complicated with acute appendicitis from March 2014 to March 2016 were retrospectively analyzed. Results 38 cases of incision infection occurred in 159 cases of diabetes mellitus complicated with acute appendicitis, the infection rate was 23.900.A total of 46 pathogenic bacteria were isolated, of which 29 strains were Gram-negative bacteria (29 strains), 17 strains were Gram-positive bacteria (36.96C), the other were Escherichia coli. Both Pseudomonas aeruginosa and Staphylococcus aureus showed higher resistance to ampicillin and piperacillin (all 70.002%). 蠂 2 test showed that incision infection and age, type of appendicitis, length of stay, preoperative blood sugar, postoperative wound infection and age of diabetes mellitus complicated with acute appendicitis, Logistic regression analysis showed that age, type of appendicitis, postoperative blood glucose and operative time were the independent risk factors of postoperative incision infection in diabetic patients with acute appendicitis. Conclusion Gram-negative bacteria is the main wound infection of diabetes mellitus complicated with acute appendicitis after operation. The drug resistance is more serious and the risk factors are many. The clinical prevention and control measures should be taken according to the results of drug sensitivity test and related factors.
【作者單位】： 河南省焦作市人民醫(yī)院普外一科;
【分類號】：R587.1;R656.8

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