本文選題：骨質(zhì)疏松癥 + 股骨近端　； 參考：《中國骨質(zhì)疏松雜志》2017年05期

【摘要】：骨質(zhì)疏松癥是一種以系統(tǒng)骨量、骨強(qiáng)度及骨微結(jié)構(gòu)損害為特征常導(dǎo)致骨折風(fēng)險(xiǎn)增加的疾病,是絕經(jīng)后婦女常見且嚴(yán)重的情況。骨質(zhì)疏松癥在骨折發(fā)生前大多是一種隱性疾病,存在著檢測(cè)和治療不足的情況。而骨質(zhì)疏松性骨折的發(fā)生常導(dǎo)致疼痛、畸形、活動(dòng)障礙,對(duì)患者的生活質(zhì)量造成嚴(yán)重影響。絕經(jīng)后骨質(zhì)疏松癥是一種好發(fā)于中老年女性的全身性骨骼系統(tǒng)疾病。眾所周知,雌激素是一種維持正常骨量的重要保護(hù)因素。絕經(jīng)后婦女體內(nèi)雌激素水平的降低與骨量的迅速流失密切相關(guān)。在婦女絕經(jīng)之后,骨重建增加,內(nèi)在的不平衡加速了骨質(zhì)流失,最終導(dǎo)致骨質(zhì)疏松癥的形成。干預(yù)絕經(jīng)后骨質(zhì)疏松癥的最主要的目的是防止骨折。最常發(fā)生骨質(zhì)疏松性骨折的部位是椎體(脊柱)、股骨近端(髖部)及前臂遠(yuǎn)端(腕部)。其中,髖部骨折是骨質(zhì)疏松癥最嚴(yán)重的后果,往往導(dǎo)致重大殘疾和過早死亡。鑒于絕經(jīng)后骨質(zhì)疏松癥的特殊性及髖部骨折的嚴(yán)重性,系統(tǒng)全面地了解絕經(jīng)后骨質(zhì)疏松癥對(duì)股骨近端的影響顯得尤為重要。
[Abstract]:Osteoporosis is a common and serious condition in postmenopausal women, characterized by bone mass, bone strength and bone microstructural damage, which often lead to an increased risk of fracture. Osteoporosis is a recessive disease before fracture, and there is insufficient detection and treatment. Osteoporosis fractures often lead to pain, deformities and dyskinesia, which have a serious impact on the quality of life of patients. Postmenopausal osteoporosis is a systemic skeletal system disease that occurs in middle-aged women. Estrogen is known to be an important protective factor in maintaining normal bone mass. The decrease of estrogen level in postmenopausal women is closely related to the rapid loss of bone mass. Bone remodeling increases after menopause, and internal imbalances accelerate bone loss, leading to osteoporosis. The main purpose of intervention in postmenopausal osteoporosis is to prevent fractures. The most common sites of osteoporotic fractures are vertebrae (spinal column, proximal femur (hip), and distal forearm (wrist). Among them, hip fracture is the most serious consequence of osteoporosis, often leading to major disability and premature death. In view of the particularity of postmenopausal osteoporosis and the severity of hip fracture, it is particularly important to understand the impact of postmenopausal osteoporosis on the proximal femur.
【作者單位】： 蚌埠醫(yī)學(xué)院第一附屬醫(yī)院;
【分類號(hào)】：R580

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