CBP聯(lián)合早期腸內(nèi)營養(yǎng)治療SAP合并高脂血癥的效果分析
發(fā)布時(shí)間:2018-04-27 20:13
本文選題:急性重癥胰腺炎 + 高脂血癥 ; 參考:《重慶醫(yī)學(xué)》2017年09期
【摘要】:目的觀察連續(xù)性血液凈化(CBP)聯(lián)合早期腸內(nèi)營養(yǎng)(EEN)治療急性重癥胰腺炎(SAP)合并高脂血癥患者的效果。方法選擇該院2014年1月至2015年10月收治的SAP合并高脂血癥患者56例,按照隨機(jī)數(shù)字表法分為CBP加EEN組(聯(lián)合組)和CBP組各28例,CBP組采用CBP治療,聯(lián)合組在CBP組的基礎(chǔ)上聯(lián)合EEN(入院后2d內(nèi))治療。治療后觀察兩組患者臨床療效及各項(xiàng)指標(biāo)改善情況。結(jié)果治療后聯(lián)合組總有效率(96.43%)高于CBP組(75.00%),兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);兩組治療后三酰甘油(TG)、尿淀粉酶(UAMY)、血脂肪酶(LPS)、血淀粉酶(SAMY)、C反應(yīng)蛋白(CRP)、乳酸脫氫酶(LDH)等相關(guān)指標(biāo)均有下降,其中聯(lián)合組較CBP組下降更明顯(P0.05)。治療后聯(lián)合組急性生理學(xué)與慢性健康狀況評分系統(tǒng)Ⅱ(APACHE-Ⅱ)評分明顯低于CBP組(P0.05),聯(lián)合組癥狀緩解時(shí)間及住院時(shí)間均短于CBP組(P0.05);聯(lián)合組并發(fā)癥發(fā)生率(10.71%)明顯低于CBP組(28.57%),兩組比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 CBP聯(lián)合早期EEN可明顯改善SAP患者的預(yù)后,有效減低患者并發(fā)癥。
[Abstract]:Objective to observe the effect of continuous blood purification (CBP) combined with early enteral nutrition (EEN) in the treatment of severe acute pancreatitis (SAP) with hyperlipidemia. Methods from January 2014 to October 2015, 56 SAP patients with hyperlipidemia were randomly divided into CBP plus EEN group (combined group) and CBP group (28 cases) treated with CBP. The combined group was treated with EEN (within 2 days after admission) on the basis of CBP. The clinical curative effect and the improvement of each index were observed after treatment. Results the total effective rate of the combined group (96.43) was higher than that of the CBP group (75.00%), and the difference between the two groups was statistically significant (P 0.05), and the related indexes such as triacylglycerol, urine amylase (UAMYN), lipase (LPSN), serum amylase SAMYC-reactive protein (CRPN) and lactate dehydrogenase (LDH) were all decreased after treatment. The decrease of P0. 05 in the combined group was more obvious than that in the CBP group. After treatment, the score of acute physiology and chronic health status scoring system 鈪,
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