發(fā)布時間：2018-04-17 11:08

  本文選題：膝骨關(guān)節(jié)炎 + 骨質(zhì)疏松癥��； 參考：《廣西中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:調(diào)查膝骨關(guān)節(jié)炎合并骨質(zhì)疏松癥患者生存質(zhì)量狀況,分析影響患者生存質(zhì)量的相關(guān)因素,以期提高整個膝骨關(guān)節(jié)炎合并骨質(zhì)疏松癥患者的生存質(zhì)量;指導(dǎo)治療方案,為社區(qū)醫(yī)療提供更多可靠的方案;為臨床工作提供理論基礎(chǔ),填補地方流行病學(xué)數(shù)據(jù)庫。方法:采用SF-36量表結(jié)合生活習(xí)慣、醫(yī)療等信息的調(diào)查表,對廣西中醫(yī)藥大學(xué)第一附屬醫(yī)院門診或住院就診已經(jīng)確診為膝骨關(guān)節(jié)炎合并骨質(zhì)疏松癥患者,展開發(fā)病后的生存質(zhì)量的問卷調(diào)查,收集相關(guān)資料并錄入數(shù)據(jù)庫,采用方差分析、t檢驗、多元回歸逐步分析等統(tǒng)計學(xué)方法對患者生存質(zhì)量狀況可能相關(guān)因素進行分析。結(jié)果:本研究調(diào)查的KOA合并OP病人生存質(zhì)量總分均值與標(biāo)準(zhǔn)差為60.04±11.022。其中各維度的評分情況分別為:一般健康狀態(tài)(GH)得分為54.77±8.213;生理機能狀態(tài)(PF)得分為61.61±13.902;生理職能狀態(tài)(RP)得分為57.08±11.542;情感職能狀態(tài)(RE)得分為72.64±19.180;社會功能狀態(tài)(SF)得分為64.92±18.965;軀體疼痛狀態(tài)(BP)得分為72.05±12.648;活力狀態(tài)(VT)得分為54.20±17.854;精神健康狀態(tài)(RP)得分為64.64±14.631。本次調(diào)查發(fā)現(xiàn),年齡與一般健康、生理機能、生理職能、社會功能、精神健康、量表總分維度呈負(fù)向相關(guān);性別與生理機能、生理職能、活力狀態(tài)、量表總分維度呈負(fù)向相關(guān),與社會功能維度呈正向相關(guān);體重指數(shù)與生理功能維度呈負(fù)相關(guān),在其它維度差異不明顯,無統(tǒng)計學(xué)意義;體育鍛煉與生理職能維度呈正相關(guān),在其它維度無統(tǒng)計學(xué)意義;職業(yè)與生理職能維度呈負(fù)相關(guān),在其它維度無統(tǒng)計學(xué)意義;文化教育程度、日照與八個維度及量表總分均無統(tǒng)計學(xué)意義;KOA累及單側(cè)還是雙側(cè)與一般健康、生理職能、精神健康維度呈負(fù)相關(guān);既往疾病與社會功能維度呈負(fù)相關(guān);吃水果蔬菜與一般健康、生理職能、情感職能、活力狀態(tài)、精神健康、量表總分呈正相關(guān);吃海產(chǎn)品與活力狀態(tài)成正比,在其它維度無統(tǒng)計學(xué)意義;吃豆制品與生理情感職能、精神狀況、社會功能維度呈負(fù)相關(guān);喝牛奶與一般健康維度呈正相關(guān),與生理職能、軀體疼痛、量表總分呈負(fù)相關(guān),在其它維度差異不顯著,無統(tǒng)計學(xué)意義;喝咖啡與生理職能、量表總分維度呈正相關(guān),在其它維度無統(tǒng)計學(xué)意義;吸煙與生理機能、生理職能、情感職能、社會功能維度呈負(fù)面影響;飲酒與生理職能維度呈正相關(guān),與社會功能維度呈負(fù)相關(guān)。結(jié)論:膝骨關(guān)節(jié)炎合并骨質(zhì)疏松癥病人的生存質(zhì)量尚處于較低水平,對生存質(zhì)量的影響也是生理、心理、社會等多層面的,各維度受影響的大小依次為情感職能軀體疼痛社會功能精神健康生理機能生理職能一般健康活力狀態(tài)�；颊呱钯|(zhì)量總分以及各維度影響較大的因素是骨密度(腰椎)、年齡、性別、蔬菜水果攝入、吸煙、單雙膝發(fā)病(OA累及單側(cè)或雙側(cè)膝關(guān)節(jié))、牛奶的攝入、豆制品攝入、飲酒、喝咖啡等。其中保護因素為腰椎骨密度、吃蔬菜水果、體育鍛煉、攝入適量海產(chǎn)品,有利于病人生存質(zhì)量的改善;危險因素為年齡、性別、吸煙、體重指數(shù)、體力相關(guān)職業(yè)、攝入過量咖啡和酒精、既往病史,可降低KOA合并OP患者的生存質(zhì)量;不確定因素為牛奶的攝入、豆制品、單雙膝發(fā)病、民族、文化程度、日照,尚需要進一步大樣本的研究證實。
[Abstract]:Objective: To investigate the knee osteoarthritis patients with osteoporosis in the quality of life, to analyze the factors affecting the quality of life of the patients, in order to improve the quality of life of patients with knee osteoarthritis and osteoporosis; therapy for community health, provide more reliable solution; provide theoretical basis for clinical work, fill the local epidemiological database. Methods: the combination of SF-36 scale and living habits, medical information on outpatient questionnaire, the First Affiliated Hospital of Guangxi TCM university or hospital treatment has been diagnosed with knee osteoarthritis and osteoporosis, investigation of quality of life after the onset of the related data were collected and entered into the database, using variance analysis, t test and multiple stepwise regression analysis on quality of life in patients with possible related factors analysis and other statistical methods. Results: the research Check the KOA and OP patients quality of life score and the standard deviation is 60.04 + 11.022. the score of each dimension are: general state of Health (GH) score was 54.77 + 8.213; physiological function status (PF) score was 61.61 + 13.902; physiological function status (RP) score was 57.08 + 11.542; emotional function status (RE) score was 72.64 + 19.180; social function (SF) score was 64.92 + 18.965; state body pain (BP) score was 72.05 + 12.648; activity status (VT) score was 54.20 + 17.854; mental health status (RP) score was 64.64 + 14.631. found in the survey, age and general health, physiological function, physiological function, social function, mental health, the total scores of dimensions are negatively correlated; gender and physiological function, physiological function, vitality, the total scores of dimensions are negatively correlated, showed a positive correlation with social function dimension; body mass index and physiological function dimension Negative correlation, in other dimensions have no significant difference, no statistical significance; the dimension of sports exercise and physiological function were positively correlated, but no significant difference was found in other dimensions; negative correlation dimension of occupation and physiological function, no significant differences in other dimensions; cultural education, sunshine and eight dimensions and the total scores were not statistically meaning; KOA involved unilateral or bilateral and general health, physiological function, mental health dimensions were negatively correlated; negatively related to medical and social function dimensions; eat fruits and vegetables and general health, physical function, emotional function, mental health, vitality, scores were positively correlated; eat seafood and energy is proportional to the state, no statistical significance in other dimensions; eat soy products and physiological and emotional function, mental health, social function dimension was negatively correlated; drink milk showed positive correlation with the general health and physiological functions of the body dimensions. The pain scores were negatively correlated, no significant differences in other dimensions, no statistical significance; coffee and physiological functions, scores were positively correlated, with no difference in other dimensions; smoking and physiological function, physiological function, emotional function, social function dimension has negative influence; alcohol consumption was positively correlated with the physiology the function dimension was negatively correlated with the social function dimension. Conclusion: the quality of life of patients with knee osteoarthritis and osteoporosis is still at a relatively low level, influence the quality of life of psychological and physical, social, and other aspects of the various dimensions of the affected order of emotional function mental health social function of physiological body pain the physiology function of general health vitality. The quality of life of patients with total scores and each dimension of the influence factors on bone mineral density (lumbar), age, gender, smoking, intake of vegetables, fruit, single and double knee disease (OA with unilateral or bilateral knee joint), milk intake, intake of bean products, alcohol, coffee and so on. The protective factors for bone mineral density, eating fruits and vegetables, physical exercise, adequate intake of seafood, is conducive to improve the quality of life of patients; risk factors as age, gender, smoking, body mass index, physical the related occupation, excessive intake of coffee and alcohol, past medical history, can reduce the quality of life of patients with KOA OP; uncertain factors for milk intake, bean products, single and double knee disease, nationality, culture degree, sunshine, still needs further study with large sample confirmed.

【學(xué)位授予單位】：廣西中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R580;R684.3

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