本文選題：維吾爾族　切入點：尿碘　出處：《新疆醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:研究新疆城鄉(xiāng)兩地區(qū)維吾爾族居民碘營養(yǎng)狀況、甲狀腺疾病及二者相關(guān)因素分析。方法:于2015年8月在新疆托克遜地區(qū)(B組)采用隨機(jī)整群抽樣方法抽取1383人,資料完整者1285人,其中成年人共1196人,平均年齡(44.12±15.0)歲,8~10歲的兒童89人。2015年10月在新疆烏魯木齊市天山區(qū)(A組)采用同樣的抽樣方法抽取2187人,資料完整者1976,其中成年人共1740人,平均年齡(42.24±15.46)歲,8~10歲的兒童共236人。通過問卷調(diào)查、食物模型及三日稱量記賬法對居民日常富碘飲食及每日食鹽攝入量調(diào)查。同時采集食用鹽、飲用水和一次尿樣及血標(biāo)本,分別測定鹽碘、水碘和尿碘、促甲狀腺激素(TSH)、甲狀腺過氧化物酶抗體(TPOAb)、甲狀腺球蛋白抗體(TgAb),TSH異常者測定FT3、FT4。結(jié)果:(1)兩地區(qū)維吾爾族居民日常膳食中攝入富碘食物均較少,其中農(nóng)村地區(qū)較城市更少(?2=7.715,P=0.005),A組成人尿碘中位數(shù)為128.78ug/L,兒童尿碘中位數(shù)為244.27ug/L,B組成人尿碘中位數(shù)為171.2 ug/L,兒童尿碘中位數(shù)為292.17ug/L,兩組各年齡段均有不同程度碘缺乏及碘過量。(2)不同文化水平、年齡、性別尿碘分布有所不同。(3)農(nóng)村碘營養(yǎng)狀況較城市良好。(4)甲狀腺功能異常者共458人,城市患病率高于農(nóng)村。(5)兩地區(qū)logistic回歸分析發(fā)現(xiàn)性別、年齡、吸煙、碘過量是甲狀腺功能異常的危險因素。(6)根據(jù)碘營養(yǎng)狀況分組,兩地區(qū)碘過量組亞甲減患病率最高。結(jié)論:兩地區(qū)加碘鹽實施達(dá)標(biāo),但仍有部分居民處于碘缺乏狀態(tài),需跟蹤隨訪。針對甲狀腺疾病易感人群需進(jìn)行甲狀腺疾病隨訪,對于可控危險因素應(yīng)積極避免。
[Abstract]:Objective: to study the iodine nutrition status, thyroid disease and related factors of Uygur population in urban and rural areas of Xinjiang.Methods: in August 2015, 1383 individuals were sampled by random cluster sampling in Group B of Tok Xun region, Xinjiang. The data were complete in 1285 people, including 1196 adults.The daily iodine rich diet and salt intake of residents were investigated by questionnaire, food model and 3-day weighing and accounting method.Salt, drinking water, primary urine samples and blood samples were collected at the same time. Salt iodine, water iodine and urine iodine, thyroid stimulating hormone TSH, thyroid peroxidase antibody TPOAbA, thyroid globulin antibody TgAbn TSH were measured respectively.Results (1) the Uygur residents in the two regions had less iodine rich food in their daily diet.(II) different levels of culture,The distribution of urinary iodine was different in age and sex. (3) the iodine nutritional status in rural area was better than that in urban area. There were 458 people with abnormal thyroid function. The prevalence rate in urban area was higher than that in rural area. Logistic regression analysis showed that sex, age and smoking.Iodine excess is the risk factor of thyroid dysfunction. 6) according to the iodine nutritional status, the prevalence of hypothyroidism was the highest in the iodine excess group.Conclusion: the implementation of iodized salt in the two areas is up to the standard, but some residents are still in iodine deficiency, which should be followed up.Thyroid disease should be followed up for the susceptible population, and controllable risk factors should be avoided.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R581

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