本文選題：粉塵螨　切入點：過敏原　出處：《廈門大學(xué)學(xué)報(自然科學(xué)版)》2017年01期

【摘要】：為了解粉塵螨(Dermatophagoides farinae)過敏患者對粉塵螨單組分過敏原Der f 1和Der f 2特異性IgE的水平情況,收集了80例疑似塵螨過敏患者樣本,對ImmunoCAP過敏原檢測系統(tǒng)和浙江大學(xué)迪迅粉塵螨檢測試劑盒檢測的粉塵螨特異性IgE陽性樣本,進一步檢測其粉塵螨單組分過敏原Der f 1和Der f 2特異性IgE水平.80例樣本中2種方法檢測粉塵螨均為陽性的有65例,陽性率為81.3%.65例陽性樣本中,Der f 1陽性率為87.7%,Der f 2陽性率為90.8%,二者至少一個為陽性的達96.99%,Der f 2特異性IgE水平顯著高于Der f 1.兒童的粉塵螨及其2種單組分過敏原Der f 1和Der f 2特異性IgE水平顯著高于成人.綜上,Der f 1和Der f 2這2種組分過敏原在我國粉塵螨患者中占據(jù)了主導(dǎo)地位,兩者特異性IgE水平存在顯著差異,后者高于前者,且兒童的敏感性顯著高于成人.
[Abstract]:In order to understand the specific IgE levels of Dermatophagoides farinaeus allergen Der f 1 and Der f 2 in patients with Dermatophagoides farinae, 80 samples of suspected dust mite allergies were collected.The specific IgE positive samples of Dermatophagoides farinae detected by ImmunoCAP allergen detection system and Dishon Dermatophagoides farinae detection kit of Zhejiang University were analyzed.The specific IgE levels of Der f1 and Der f 2 were further detected in 65 of the 80 samples of Dermatophagoides farinae.The positive rate of Der f1 was 87.7% and the positive rate of Der f2 was 90.8. The specific IgE level of Der f2 was significantly higher than that of Der f1 in at least one of them.The specific IgE levels of Der f 1 and Der f 2 were significantly higher in children than in adults.The allergens of Der f 1 and Der f 2 played a dominant role in the patients with Dermatophagoides farinae in China. There was a significant difference in the specific IgE levels between them. The latter was higher than the former, and the sensitivity of children was significantly higher than that of adults.
【作者單位】： 浙江大學(xué)醫(yī)學(xué)院附屬邵逸夫醫(yī)院;
【基金】：浙江省重大(重點)國際科技合作項目(2009C14029)
【分類號】：R593.1

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