本文選題：雌激素　切入點(diǎn)：骨標(biāo)志物　出處：《中國老年學(xué)雜志》2017年02期

【摘要】：目的探討雌激素和骨標(biāo)志物與絕經(jīng)后婦女骨質(zhì)疏松(OP)的關(guān)系。方法絕經(jīng)后OP婦女71例為觀察組,同期絕經(jīng)后無OP婦女71例為對照組,行雌激素和骨標(biāo)志物檢測并分析其與絕經(jīng)后婦女OP的相關(guān)性。結(jié)果觀察組雌二醇、孕酮、骨密度值低于對照組(P0.05)。觀察組促卵泡成熟激素、促黃體生成激素、β-膠原降解產(chǎn)物、總骨Ⅰ型前膠原氨基酸延長鏈、骨鈣素N端中分子高于對照組(P0.05)。雌二醇、孕酮、骨密度值與OP呈明顯負(fù)相關(guān)。促卵泡成熟激素、促黃體生成激素、β-膠原降解產(chǎn)物、總骨Ⅰ型前膠原氨基酸延長鏈、骨鈣素N端中分子與OP呈明顯正相關(guān)。結(jié)論雌激素和骨標(biāo)志物與絕經(jīng)后婦女OP的關(guān)系密切。監(jiān)測雌激素和骨標(biāo)志物可及早發(fā)現(xiàn)骨代謝異常,有助于防治絕經(jīng)后婦女OP。
[Abstract]:Objective to investigate the relationship between estrogen and bone markers and osteoporosis (OPN) in postmenopausal women.Methods 71 postmenopausal op women as observation group and 71 postmenopausal non-op women as control group. Estrogen and bone markers were detected and their correlation with op in postmenopausal women was analyzed.Results the values of estradiol, progesterone and bone mineral density in the observation group were lower than those in the control group (P 0.05).In the observation group, follicle maturation hormone, luteinizing hormone, 尾 -collagen degradation product, amino acid chain of total procollagen 鈪，

本文編號：1707958