本文選題：BMI指數(shù)　切入點(diǎn)：型糖尿病　出處：《重慶醫(yī)學(xué)》2017年16期

【摘要】：目的探討不同體質(zhì)量指數(shù)(BMI)的2型糖尿病患者心血管等靶器官功能損傷的風(fēng)險(xiǎn)。方法自2014年1月至2016年1月前瞻性收集該院收治的2型糖尿病患者126例,其中研究組(BMI≥25kg/m2)57例,對(duì)照組(18.5kg/m2≤BMI25kg/m2)69例。分析兩組患者的臨床特征,并分析BMI與靶器官損傷相關(guān)指標(biāo)[頸動(dòng)脈內(nèi)膜中膜厚度(IMT)、動(dòng)脈硬化指數(shù)、冠心病指數(shù)和腎小球?yàn)V過(guò)率]的相關(guān)性。結(jié)果兩組患者空腹血糖差異無(wú)統(tǒng)計(jì)學(xué)意義(P=0.953),研究組患者BMI顯著高于對(duì)照組(P=0.000)。與對(duì)照組比較,研究組患者年齡顯著增加(P=0.038);收縮壓顯著增加(P=0.000);糖尿病家族史顯著增加(P=0.000);總膽固醇顯著增加(P=0.012);三酰甘油顯著增加(P=0.000);高密度脂蛋白顯著降低(P=0.003);HOMA-IR水平顯著升高(P=0.000);HOMA-β水平顯著降低(P=0.000);IMT水平顯著升高(P=0.000);動(dòng)脈硬化指數(shù)顯著升高(P=0.000);冠心病指數(shù)顯著升高(P=0.001);腎小球?yàn)V過(guò)率顯著降低(P=0.000)。Pearson直線相關(guān)分析顯示BMI與IMT、動(dòng)脈硬化指數(shù)、冠心病指數(shù)和腎小球?yàn)V過(guò)率相關(guān),r值分別為0.234、0.257、0.294和0.211(均P=0.000)。結(jié)論 2型糖尿病患者BMI水平與心血管和腎功能損傷有關(guān)。
[Abstract]:Objective to investigate the risk of cardiovascular and other target organ dysfunction in patients with type 2 diabetes mellitus with different body mass index (BMI). Methods from January 2014 to January 2016, 126 patients with type 2 diabetes mellitus were prospectively collected. The clinical characteristics of the two groups were analyzed, and the correlation indexes between BMI and target organ injury were analyzed [carotid intima-media thickness, arteriosclerosis index, arteriosclerosis index, carotid intima media thickness, arteriosclerosis index]. Results there was no significant difference in fasting blood glucose between the two groups. The BMI of the study group was significantly higher than that of the control group. The age of the patients in the study group was significantly increased, the systolic blood pressure increased significantly, the systolic blood pressure increased significantly; the family history of diabetes increased significantly; the total cholesterol increased significantly; the total cholesterol increased significantly; the triglyceride increased significantly; the level of high density lipoprotein decreased significantly; the level of HOMA-IR increased significantly; the level of HOMA- 尾 increased significantly. The level of IMT increased significantly; the arteriosclerosis index increased significantly; the coronary heart disease index increased significantly; the glomerular filtration rate decreased significantly; and the linear correlation analysis showed that BMI was significantly associated with IMT and arteriosclerosis index. Coronary heart disease index (CHD) and glomerular filtration rate (GFR) were 0.234 and 0.217 respectively (P < 0.001). Conclusion the BMI level in type 2 diabetic patients is related to cardiovascular and renal function damage.
【作者單位】： 浙江省臺(tái)州市第一人民醫(yī)院內(nèi)分泌科;
【分類號(hào)】：R587.2
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本文編號(hào)：1673957