本文選題：骨質(zhì)疏松　切入點：低強度脈沖超聲　出處：《科學通報》2016年26期

【摘要】：骨質(zhì)疏松癥是一種全身性骨骼系統(tǒng)疾病,以骨量減少、骨微結(jié)構(gòu)退化為主要特征,常伴有骨痛、駝背、骨折等癥狀,嚴重影響患者生活質(zhì)量.目前骨質(zhì)疏松治療以藥物治療為主,但副作用較大.物理療法低強度脈沖超聲(LIPUS)則可以避免藥物不良反應,且具有無創(chuàng)傷、無電離輻射等優(yōu)點.研究表明,LIPUS刺激在骨折愈合中具有積極作用,而骨折和骨質(zhì)疏松治療時某些生物機制相似,因此LIPUS可能是治療骨質(zhì)疏松的重要潛在手段.本文通過查閱以"LIPUS"、"骨折"、"骨質(zhì)疏松"為主題的大量相關(guān)資料并進行歸納總結(jié),從骨組織結(jié)構(gòu)與功能、LIPUS治療骨病的生物學機制以及LIPUS治療骨質(zhì)疏松的實驗研究入手,分析論證LIPUS治療骨質(zhì)疏松的有效依據(jù),對LIPUS治療骨質(zhì)疏松研究現(xiàn)狀進行綜述,以期為治療骨質(zhì)疏松提供新的思路和理論依據(jù).
[Abstract]:Osteoporosis is a systemic skeletal system disease characterized by reduced bone mass and degeneration of bone microstructure, often accompanied by bone pain, humpback, fracture, etc. At present, the main treatment for osteoporosis is drug therapy, but the side effects are larger. Physical therapy with low intensity pulsed ultrasound (LIPUS) can avoid adverse drug reactions and has no trauma. Studies have shown that LIPUS stimuli play a positive role in fracture healing, while some biological mechanisms are similar in the treatment of fractures and osteoporosis. Therefore, LIPUS may be an important potential method for the treatment of osteoporosis. In this paper, a large number of related data on the topics of "LIPUS", "fracture" and "osteoporosis" were reviewed and summarized. Based on the biological mechanism of bone tissue structure and function and the experimental study of LIPUS in the treatment of osteoporosis, this paper analyzes and proves the effective basis of LIPUS in the treatment of osteoporosis, and summarizes the present research situation of LIPUS in the treatment of osteoporosis. In order to provide new ideas and theoretical basis for the treatment of osteoporosis.
【作者單位】： 復旦大學電子工程系;上海市醫(yī)學圖像處理與計算機輔助手術(shù)重點實驗室;Department
【基金】：國家杰出青年科學基金(11525416) 國家自然科學基金(11174060,11327405) 上海市科技支撐計劃(13441901900)資助
【分類號】：R580;TB559

【相似文獻】

相關(guān)期刊論文 前1條

1 顧穎弘;為地球做的事[J];世界科學;2000年03期

，

本文編號：1659462