本文選題：型糖尿病　切入點(diǎn)：惡性腫瘤　出處：《復(fù)旦學(xué)報(bào)(醫(yī)學(xué)版)》2017年05期 　論文類型：期刊論文

【摘要】：目的揭示上海市閔行區(qū)2型糖尿病(type 2 diabetes mellitus,T2DM)患者全癌種惡性腫瘤發(fā)病狀況。方法以上海市閔行區(qū)2004—2014年各社區(qū)衛(wèi)生服務(wù)中心進(jìn)行登記管理的新發(fā)T2DM患者為研究對(duì)象,采用回顧性隊(duì)列研究,于上海市惡性腫瘤登記系統(tǒng)追蹤糖尿病患者惡性腫瘤的發(fā)病情況,計(jì)算T2DM患者的惡性腫瘤發(fā)病率及與當(dāng)?shù)匾话闳巳旱膼盒阅[瘤標(biāo)準(zhǔn)化發(fā)病比(standardized incidence ratio,SIR)和95%CI。結(jié)果男性和女性T2DM患者惡性腫瘤全癌種發(fā)病率分別為969.69/10萬(wàn)和834.17/10萬(wàn)人年(person-year),世界人口年齡標(biāo)化發(fā)病率(age-standardized rate,ASR[W])分別為206.72/10萬(wàn)人年和285.80/10萬(wàn)人年,男女性全癌種惡性腫瘤的標(biāo)化發(fā)病比分別為0.93(95%CI:0.88~0.98)和1.07(95%CI:1.01~1.12)。結(jié)論與一般人群相比,T2DM患者特定癌種的發(fā)病風(fēng)險(xiǎn)增高,不同癌種的發(fā)病風(fēng)險(xiǎn)變化存在差異。
[Abstract]:Objective to reveal the incidence of type 2 diabetes mellitus type 2 diabetes mellitusus T2DM (T2DM) patients in Minhang District, Shanghai. Methods New T2DM patients who were registered and managed by community health service centers in Minhang District from 2004 to 2014 were studied. A retrospective cohort study was conducted to track the incidence of malignant tumors in patients with diabetes mellitus in Shanghai malignant tumor Registration system. The incidence of malignant tumors in T2DM patients and the standardized incidence of malignant tumors in the local population were compared with those of the local general population. Results the incidence rates of malignant tumors in male and female T2DM patients were 969.69% / 100 000 and 834.17% / 100 000, respectively. The incidence rate of malignant tumor in male and female T2DM patients was 969.69 / 100 and 834.17 / 100 million, respectively. The age-standardized incidence of ASR [W] is 206.72 / 100, 000 person-years and 285.80 / 100,000 person-years, respectively. The standardized incidence ratios of malignant tumors of male and female were 0.93 / 95 CI: 0.880.98) and 1.07i / 95 CI: 1.01C / 1.120.Conclusion compared with the general population, the risk of specific cancer in patients with T2DM is higher than that in the general population, and there are differences among different types of cancer.
【作者單位】： 上海市閔行區(qū)疾病預(yù)防控制中心;復(fù)旦大學(xué)公共衛(wèi)生學(xué)院生物統(tǒng)計(jì)學(xué)教研室;流行病學(xué)教研室;
【基金】：上海市閔行區(qū)自然科學(xué)研究課題(2016MHZ25) 上海市衛(wèi)生和計(jì)劃生育委員會(huì)科研課題(201640254) 上海市研究生教育創(chuàng)新計(jì)劃 上海市公共衛(wèi)生與預(yù)防醫(yī)學(xué)Ⅰ類高峰學(xué)科建設(shè)計(jì)劃~~
【分類號(hào)】：R587.1

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