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腎錯構(gòu)瘤破裂出血的臨床風險因素分析

發(fā)布時間:2019-05-22 12:31
【摘要】:目的探討腎錯構(gòu)瘤(RAML)破裂出血的臨床風險因素。方法收集有完整病史及腎臟影像學資料的RAML患者352例,將與錯構(gòu)瘤破裂出血可能有關(guān)的風險因素行破裂出血組和未破裂出血組間的單因素分析及多因素logistic回歸分析。結(jié)果 352例患者中有41例患者的錯構(gòu)瘤發(fā)生破裂出血,311例未發(fā)生破裂出血。通過單因素分析,發(fā)現(xiàn)年齡、有無臨床表現(xiàn)、結(jié)節(jié)性硬化癥、高血壓、瘤體是否突出腎表面、錯構(gòu)瘤大小(4 cm或≥4 cm)以及腫瘤血管是否豐富等因素在兩組間具有明顯的差異(P0.05);再通過多因素logistic回歸分析進一步發(fā)現(xiàn),有臨床表現(xiàn)(OR=36.012,P=0.000)、伴隨有結(jié)節(jié)性硬化癥(OR=25.167,P=0.004)、瘤體突出腎臟表面(OR=8.151,P=0.003)、錯構(gòu)瘤大小≥4 cm(OR=13.006,P=0.003)、腫瘤血管豐富(OR=4.272,P=0.004)等因素對破裂出血的影響有顯著的統(tǒng)計學意義。結(jié)論有臨床表現(xiàn)者、伴隨有結(jié)節(jié)性硬化癥、腫瘤外生性生長、瘤體≥4 cm以及豐富的腫瘤血管等因素可視為RAML破裂出血的高風險因素。
[Abstract]:Objective to investigate the clinical risk factors of (RAML) rupture and hemorrhage in renal hamartoma. Methods 352patients with complete history and renal imaging data were collected. The risk factors related to ruptured hemorrhage of hamartoma were analyzed by univariate analysis and multivariate logistic regression analysis between ruptured bleeding group and unruptured hemorrhage group. Results there were 41 patients with hamartoma ruptured bleeding and 311 patients without ruptured hemorrhage. Through univariate analysis, it was found that age, clinical manifestations, nodular sclerosis, hypertension and protruding renal surface were found. There were significant differences in the size of hamartoma (4 cm or 鈮,

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