【摘要】：目的: 探討泌尿外科男性住院患者前列腺特異性抗原(Prostate specific antigen,PSA)檢查的價(jià)值和臨床意義。 方法: 選取2010.12-2013.12來我科45歲以上，常規(guī)檢查PSA的男性住院患者1354例。年齡45~95歲，，平均年齡為（68±11.19）歲。排除臨床已確診前列腺癌及由于各種原因不能配合者。對(duì)1354例患者PSA的檢查結(jié)果進(jìn)行分析，PSA水平、年齡、入院診斷、出院診斷、肛門指檢、影像學(xué)檢查、穿刺病理結(jié)果等臨床資料進(jìn)行分析，探討PSA檢查的價(jià)值。 結(jié)果: 在1354例研究對(duì)象中，PSA異常共439例，PSA正常共915例，共確診前列腺癌患者91例。隨著年齡的增長(zhǎng)，前列腺癌的發(fā)病率也逐步增高，其整體差異有統(tǒng)計(jì)學(xué)意義（X2=33.827，P＜0.05），但組間差異無統(tǒng)計(jì)學(xué)意義。73例前列腺癌患者（79.3%）集中在60~79歲之間。隨著PSA水平升高，前列腺活檢的陽性率也隨之升高，其整體差異有統(tǒng)計(jì)學(xué)意義（X2=68.797，P＜0.05）。但PSA正常組與PSA異常組間的穿刺陽性率的差異無統(tǒng)計(jì)學(xué)意義。年齡與PSA水平也有一定的相關(guān)性，年齡越到，PSA水平越高。91例前列腺癌中以下尿路癥狀（lowerurinary tract symptoms,LUTS）為首發(fā)癥狀就診的患者為83例（91.2%），以非LUTS為首發(fā)癥狀就診的患者為8例（8.8%）。以良性疾病為初步診斷最終確診前列腺癌患者25例，腫瘤分期較早，以懷疑前列腺癌為初步診斷最終確診前列腺癌患者66例，腫瘤分期較晚。 結(jié)論: 泌尿外科住院患者行PSA檢查有較重要的臨床意義，對(duì)于無明顯臨床癥狀前列腺癌的早期診斷尤為重要，建議50歲以上的男性住院患者應(yīng)篩查PSA。
[Abstract]:Objective: to investigate the value and clinical significance of prostate specific antigen (Prostate specific antigen,PSA) in male inpatients in urology. Methods: 1354 male inpatients over 45 years old and undergoing routine examination of PSA were selected from December 2012 to March 12, 2013.2010.Results: 1354 male inpatients over 45 years old were enrolled in this study. The average age was (68 鹵11.19) years old. Exclude those who have been clinically diagnosed with prostate cancer and are unable to cooperate for various reasons. The clinical data of 1354 patients with PSA, such as PSA level, age, admission diagnosis, discharge diagnosis, anal finger examination, imaging examination and puncture pathological results, were analyzed to explore the value of PSA examination. Results: among 1354 subjects, 439 cases were abnormal PSA, 915 cases were normal PSA, and 91 cases were diagnosed as prostate cancer. With the increase of age, the incidence of prostate cancer also increased gradually, and the overall difference was statistically significant (X2 鈮

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