【摘要】：目的探討中國公民逝世后器官捐獻肝腎器官移植的臨床療效及初步經(jīng)驗。方法回顧性分析成功實施的8例中國公民逝世后器官捐獻供者和21例受者臨床資料、受者圍手術(shù)期情況及預(yù)后等。結(jié)果 8例供者中,屬于中國二類1例,中國三類7例。21例受者中,5例接受肝移植、15例接受腎移植和1例接受肝腎聯(lián)合移植,手術(shù)均順利完成。肝移植受者圍手術(shù)期間,1例死于術(shù)后出血、感染和多器官功能衰竭;術(shù)后隨訪時間4~25個月,生存受者均預(yù)后良好。腎移植受者圍手術(shù)期間,供者血肌酐(Cr)正常的5例,供給10例受者中2例發(fā)生移植腎功能延遲恢復(fù)(DGF),發(fā)生率20.0%;供體Cr(≥133μmol/L)異常的3例,供給5例受者4例發(fā)生DGF,發(fā)生率80.0%;術(shù)后隨訪時間5~42個月,7例發(fā)生肺部感染,2例出現(xiàn)腎功能不全,其他受者恢復(fù)順利,預(yù)后良好。1例肝腎聯(lián)合移植受者恢復(fù)良好,未出現(xiàn)重大手術(shù)及手術(shù)相關(guān)并發(fā)癥。結(jié)論合理有效地利用中國公民逝世后器官捐獻的供器官、加強供者術(shù)前評估與功能維護以及減少熱缺血和冷缺血時間,既擴大了供器官來源,又能獲得滿意的移植效果。
[Abstract]:Objective to investigate the clinical effect and preliminary experience of organ donation for liver and kidney transplantation after death of Chinese citizens. Methods the clinical data of 8 donors and 21 recipients of organ donation after the death of Chinese citizens were analyzed retrospectively. The perioperative period and prognosis of the recipients were analyzed retrospectively. Results among the 8 donors, 1 belonged to the second class in China and 7 to the third category in China. Of the 21 recipients, 5 received liver transplantation, 15 received kidney transplantation and 1 received combined liver and kidney transplantation. The operation was completed successfully. One patient died of postoperative hemorrhage, infection and multiple organ failure during perioperative period of liver transplantation, and the follow-up time was 4 ~ 25 months. During the perioperative period of renal transplantation, there were 5 cases with normal serum creatinine (Cr) in donor, and 2 cases with delayed recovery of renal function (DGF),) occurred in 2 out of 10 recipients. The incidence of delayed recovery of renal function was 20.0%. 3 cases of donor Cr (鈮，

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