4862例腎活檢患者臨床與病理資料分析
[Abstract]:Objective: to analyze retrospectively the clinical and pathological data of 4862 patients with renal biopsy, and to summarize the age and sex characteristics, the distribution of pathological types and the relationship between pathological types and clinical diagnosis. The disease spectrum of renal biopsy from 2007 to 2011 was compared in order to provide valuable data for the diagnosis and treatment of renal diseases in this area. Methods: the clinical and pathological data of 4862 patients who underwent renal biopsy from January 1, 2007 to December 31, 2016 in the Department of Nephrology, second Hospital of Jilin University were retrospectively analyzed. The data were analyzed according to sex, age, time of renal biopsy and clinical diagnosis. The distribution and changes of pathological types and the relationship between clinical diagnosis and pathological data were analyzed. Results: most of the patients were male (52.92%), the ratio of male to female was 1.12: 1. Except for secondary renal disease and hereditary nephropathy, male patients were more than female. The average age of renal biopsy patients was 41.59 鹵15.66 years old. The incidence of primary glomerular disease was the highest (73.49%), followed by secondary renal disease (23.34%). The most common pathological types of primary glomerular diseases were IgA nephropathy (32.33%) and membranous nephropathy (32.21%). Compared with 2007-2011, the detection rate of membranous nephropathy in 2012-2016 was significantly higher than that in IgA nephropathy. The most common pathological type of secondary renal disease was lupus nephritis (34.01%). The most common clinical diagnosis of renal biopsy was nephrotic syndrome (43.83%), chronic glomerulonephritis (36.20%) and chronic renal failure (13.04%). The most common pathological type of nephrotic syndrome in primary glomerular diseases is membranous nephropathy (47.78%), and the most common pathological type in secondary renal diseases is lupus nephritis. Renal biopsy can further correct the clinical diagnosis of disease. Ultrastructural pathology plays an important role in the final diagnosis of renal pathology. Conclusion: 1, the average age of renal biopsy patients in this center has an increasing trend, and the proportion of elderly renal biopsy patients is obviously increased. 2. The pathological types of renal biopsy patients are mainly primary glomerular diseases, and the incidence of membranous nephropathy is increasing year by year. The incidence of IgA nephropathy decreased year by year, and the incidence of membranous nephropathy was higher than that of IgA nephropathy in recent five years. Lupus nephritis is the most common pathological type of secondary renal disease, nephrotic syndrome and chronic glomerulonephritis are the most common clinical diagnosis of renal biopsy. Ultrastructural pathological diagnosis plays an important role in the final outcome of renal pathology.
【學(xué)位授予單位】:吉林大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R692
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