原發(fā)性腎病綜合征患者低T3綜合征的發(fā)病因素分析
發(fā)布時(shí)間:2018-12-29 10:25
【摘要】:目的分析原發(fā)性腎病綜合征(PNS)患者低T3綜合征(LT3S)的發(fā)病因素。方法 195例PNS患者按是否合并LT3S分為并發(fā)者43例(并發(fā)LT3S)和正常者152例(甲狀腺功能正常),單因素分析法比較兩者臨床資料,多因素Logistics回歸分析法分析PNS患者并發(fā)LT3S的相關(guān)因素。結(jié)果單因素分析顯示,PNS患者并發(fā)LT3S者和甲狀腺功能正常者活化部分凝血酶時(shí)間、血清白蛋白、24 h尿蛋白定量、CD36、血小板聚集率(PAg TADP、PAg TAA)比較有統(tǒng)計(jì)學(xué)差異(P均0.05)。多因素分析顯示,CD36、PAg TAA為PNS患者并發(fā)LT3S的相關(guān)因素。結(jié)論 PNS患者易并發(fā)LT3S,CD36、PAg TAA為PNS患者并發(fā)LT3S的相關(guān)因素。
[Abstract]:Objective to analyze the risk factors of low T 3 syndrome (LT3S) in patients with primary nephrotic syndrome (PNS). Methods one hundred and fifty-five patients with PNS were divided into three groups according to whether they were complicated with LT3S: 43 cases (complicated with LT3S) and 152 cases with normal thyroid function (normal thyroid function). The clinical data were compared by univariate analysis. Multivariate Logistics regression analysis was used to analyze the related factors of LT3S in PNS patients. Results univariate analysis showed that the activated partial thrombin time, serum albumin, 24 h urinary protein quantification and platelet aggregation rate of CD36, were found in patients with PNS complicated with LT3S and normal thyroid function. There was a significant difference in PAg TAA) between the two groups (P < 0. 05). Multivariate analysis showed that CD36,PAg TAA was associated with LT3S in PNS patients. Conclusion the risk of LT3S,CD36,PAg TAA in PNS patients is related to LT3S in PNS patients.
【作者單位】: 南通大學(xué)附屬醫(yī)院;
【基金】:南通市重點(diǎn)科技項(xiàng)目(MS32015018)
【分類(lèi)號(hào)】:R692
本文編號(hào):2394720
[Abstract]:Objective to analyze the risk factors of low T 3 syndrome (LT3S) in patients with primary nephrotic syndrome (PNS). Methods one hundred and fifty-five patients with PNS were divided into three groups according to whether they were complicated with LT3S: 43 cases (complicated with LT3S) and 152 cases with normal thyroid function (normal thyroid function). The clinical data were compared by univariate analysis. Multivariate Logistics regression analysis was used to analyze the related factors of LT3S in PNS patients. Results univariate analysis showed that the activated partial thrombin time, serum albumin, 24 h urinary protein quantification and platelet aggregation rate of CD36, were found in patients with PNS complicated with LT3S and normal thyroid function. There was a significant difference in PAg TAA) between the two groups (P < 0. 05). Multivariate analysis showed that CD36,PAg TAA was associated with LT3S in PNS patients. Conclusion the risk of LT3S,CD36,PAg TAA in PNS patients is related to LT3S in PNS patients.
【作者單位】: 南通大學(xué)附屬醫(yī)院;
【基金】:南通市重點(diǎn)科技項(xiàng)目(MS32015018)
【分類(lèi)號(hào)】:R692
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