發(fā)布時(shí)間：2018-11-23 13:28

【摘要】：目的:探討腎移植術(shù)后尿路感染的發(fā)生時(shí)間、主要病原菌、耐藥性及抗感染治療方案,為臨床診治提供參考。方法:將2013年1月-2015年12月因腎移植術(shù)后尿路感染來某院就診的59例患者作為研究對象,對其臨床資料進(jìn)行回顧性分析。結(jié)果:腎移植術(shù)后尿路感染的發(fā)生時(shí)間主要集中在術(shù)后6個月內(nèi),占88.14%。病原體主要為細(xì)菌和病毒,其中革蘭陰性菌感染42例,占65.63%,革蘭陽性菌感染11例,占17.19%,巨細(xì)胞病毒感染8例,占12.50%,真菌感染3例,占4.69%。經(jīng)驗(yàn)性抗感染治療藥物主要包括哌拉西林他唑巴坦、頭孢哌酮舒巴坦等。結(jié)論:腎移植術(shù)后尿路感染的發(fā)生率較高,需引起重視,應(yīng)根據(jù)患者的具體情況,合理用藥,提高治愈率。
[Abstract]:Objective: to investigate the occurrence time, main pathogenic bacteria, drug resistance and anti-infection treatment of urinary tract infection after renal transplantation, so as to provide reference for clinical diagnosis and treatment. Methods: the clinical data of 59 patients with urinary tract infection after renal transplantation from January 2013 to December 2015 were retrospectively analyzed. Results: the time of urinary tract infection after renal transplantation was mainly within 6 months after transplantation, accounting for 88.14. The pathogens were mainly bacteria and viruses, of which 42 cases were Gram-negative bacteria (65.63%), 11 cases were Gram-positive bacteria (17.19%), 8 cases were cytomegalovirus (12.50%), 3 cases were fungal infections (4.69%). Empirical anti-infection drugs include piperacillin, cefoperazone and sulbactam. Conclusion: the incidence of urinary tract infection after renal transplantation is high and should be paid attention to.
【作者單位】： 首都醫(yī)科大學(xué)附屬北京朝陽醫(yī)院藥事部;
【分類號】：R699.2

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