發(fā)布時間：2018-11-20 06:06

【摘要】：目的:探討腎�？的z囊治療腎功能不全患者的臨床療效及對腎功能指標的影響。方法:對廣西醫(yī)科大學第一附屬醫(yī)院2015年2-5月使用腎�？的z囊治療腎功能不全的住院患者100例進行回顧性分析,記錄患者一般情況、治療方案、治療前后的腎功能指標和臨床療效,并分析臨床療效與年齡、療程的關(guān)系。結(jié)果:急性腎功能不全33例,慢性腎功能不全67例。腎�？的z囊的給藥方式主要是口服給藥(97例,97.00%),劑量主要為6粒/d(36例,36.00%),療程以0~7 d(39例)和7~15 d(49例)為主。治療后,所有患者的血清肌酐水平較治療前顯著降低,腎小球濾過率、內(nèi)生肌酐清除率較治療前顯著升高,差異有統(tǒng)計學意義(P0.05)�；颊呖傆行蕿�72.00%,其中急性腎功能不全患者有效率為87.88%,顯著高于慢性腎功能不全患者的64.18%,差異有統(tǒng)計學意義(P0.05)�！�60歲患者中,急性腎功能不全患者的總有效率顯著高于慢性腎功能不全患者,差異有統(tǒng)計學意義(P0.05);60歲急、慢性腎功能不全患者療效比較,差異無統(tǒng)計學意義(P0.05);慢性腎功能不全患者中,60歲患者的總有效率顯著高于≤60歲患者,差異有統(tǒng)計學意義(P0.05)。隨著療程延長,急性腎功能不全患者的總有效率呈上升趨勢,慢性腎功能不全患者的總有效率先升高后下降。所有患者治療期間均未見明顯不良反應的發(fā)生。結(jié)論:腎�？的z囊可改善腎功能不全患者的腎功能,對急性腎功能不全患者臨床療效優(yōu)于慢性腎功能不全患者,且安全性好;其臨床療效可能與年齡、療程有關(guān)。
[Abstract]:Objective: to investigate the effect of Shenfukang capsule on renal function index. Methods: 100 inpatients with renal insufficiency were treated with Shenfukang capsule from February to May 2015 in the first affiliated Hospital of Guangxi Medical University. The indexes of renal function and clinical efficacy before and after treatment were analyzed, and the relationship between clinical efficacy and age and course of treatment was analyzed. Results: there were 33 cases of acute renal insufficiency and 67 cases of chronic renal insufficiency. Shenfukang capsule was administered orally (97 cases, 97.00%), the dosage was mainly 6 tablets / d (36 cases, 36.00%). The course of treatment was 0 days (39 cases) and 715 days (49 cases). After treatment, the serum creatinine level of all patients was significantly lower than before treatment, glomerular filtration rate, creatinine clearance rate was significantly higher than before treatment, the difference was statistically significant (P0.05). The total effective rate was 72.00, in which the effective rate of acute renal insufficiency was 87.88, which was significantly higher than that of chronic renal insufficiency (64.18). The difference was statistically significant (P0.05). The total effective rate of patients with acute renal insufficiency was significantly higher than that of patients with chronic renal insufficiency (P0.05). There was no significant difference in the curative effect of 60 years old patients with acute renal failure and chronic renal insufficiency patients (P0.05); the total effective rate of 60 years old patients with chronic renal insufficiency was significantly higher than that of 鈮，

本文編號：2344002