心踝血管指數(shù)對(duì)腹膜透析患者動(dòng)脈硬化的預(yù)測(cè)價(jià)值及相關(guān)影響因素
發(fā)布時(shí)間:2018-10-24 14:16
【摘要】:目的評(píng)估心踝血管指數(shù)在腹膜透析患者動(dòng)脈硬化中的應(yīng)用價(jià)值及相關(guān)影響因素。方法選擇95例維持性腹膜透析患者,收集患者的基本信息和實(shí)驗(yàn)室指標(biāo),同時(shí)測(cè)定患者的心踝血管指數(shù)(CAVI)。根據(jù)CAVI是否升高分為高CAVI組(CAVI≥9)和正常CAVI組(CAVI9)。結(jié)果高CAVI組CAVI(9.85±0.73)明顯高于正常CAVI組(7.67±0.81),高CAVI組年齡(54.64±5.68歲)、透析時(shí)間(48.32±30.43月)、脈壓(57.41±12.43 mm Hg)、血清矯正鈣(2.52±0.28 mmol/L)、血磷(2.22±0.66 mmol/L)、鈣磷乘積(5.59±1.70)、空腹血糖(6.02±1.83 mmol/L)明顯高于正常CAVI組,血紅蛋白(83.96±20.53 g/L)、血白蛋白(32.40±5.22 g/L)明顯低于正常CAVI組。Spearman相關(guān)分析顯示腹膜透析患者CAVI與年齡、透析時(shí)間、脈壓、血清矯正鈣、血磷、鈣磷乘積、空腹血糖、高敏C反應(yīng)蛋白呈正相關(guān)(r值分別為0.520、0.260、0.244、0.347、0.231、0.338、0.225、0.298,P均0.05),與血白蛋白、25-羥維生素D呈負(fù)相關(guān)(r值分別為-0.335、-0.222,P均0.05);多元線性回歸分析顯示年齡、血白蛋白是腹膜透析患者CAVI的獨(dú)立危險(xiǎn)因素。結(jié)論心踝血管指數(shù)可以作為評(píng)價(jià)腹膜透析患者動(dòng)脈硬化的無(wú)創(chuàng)檢測(cè)指標(biāo),早期檢測(cè)心踝血管指數(shù)、改善營(yíng)養(yǎng)狀況可以降低腹膜透析患者動(dòng)脈硬化發(fā)生風(fēng)險(xiǎn),減少心血管疾病的發(fā)生,改善預(yù)后。
[Abstract]:Objective to evaluate the clinical value of malleolus index in peritoneal dialysis patients with arteriosclerosis. Methods 95 patients with maintenance peritoneal dialysis were selected and their basic information and laboratory parameters were collected. Meanwhile, the cardiac and ankle vascular index (CAVI).) was measured. According to whether CAVI increased or not, high CAVI group (CAVI 鈮,
本文編號(hào):2291642
[Abstract]:Objective to evaluate the clinical value of malleolus index in peritoneal dialysis patients with arteriosclerosis. Methods 95 patients with maintenance peritoneal dialysis were selected and their basic information and laboratory parameters were collected. Meanwhile, the cardiac and ankle vascular index (CAVI).) was measured. According to whether CAVI increased or not, high CAVI group (CAVI 鈮,
本文編號(hào):2291642
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