上尿路結(jié)石梗阻合并高血壓患者解除梗阻后血壓變化及其影響因素分析
發(fā)布時(shí)間:2018-08-13 20:14
【摘要】:目的:探討上尿路結(jié)石梗阻合并高血壓患者解除梗阻后血壓動(dòng)態(tài)變化及其影響因素,為臨床治療提供一定的理論和指導(dǎo)依據(jù)。方法:以2014年7月至2016年12月在遵義醫(yī)學(xué)院附屬醫(yī)院行手術(shù)治療的110例上尿路結(jié)石梗阻合并高血壓患者為研究對(duì)象,收集研究對(duì)象術(shù)前到術(shù)后1月的血壓情況。單因素比較患者性別、年齡、結(jié)石類型、手術(shù)方式、梗阻時(shí)間、腎臟積水程度、結(jié)石分布、結(jié)石大小、高血壓分級(jí)、腎素(PRA)及血管緊張素Ⅱ(AngⅡ)值等對(duì)上尿路結(jié)石致高血壓患者術(shù)后血壓恢復(fù)率的影響差異(χ2檢驗(yàn),P0.05),篩選出單因素分析有統(tǒng)計(jì)學(xué)意義的變量用Logistic回歸分析法進(jìn)行多因素分析影響上尿路結(jié)石梗阻合并高血壓患者術(shù)后血壓恢復(fù)的危險(xiǎn)因素。分別比較不同梗阻時(shí)間、腎臟積水程度、PRA及AngⅡ值患者術(shù)后收縮壓和舒張壓下降程度(t檢驗(yàn),P0.05)。結(jié)果:在單因素分析統(tǒng)計(jì)分析中,不同結(jié)石梗阻時(shí)間、腎臟積水程度、PRA及AngⅡ值正常與否各組患者術(shù)后1月血壓恢復(fù)率差異有統(tǒng)計(jì)學(xué)意義(P0.05);患者性別、年齡、結(jié)石類型、手術(shù)方式、結(jié)石大小、結(jié)石分布、高血壓分級(jí)與術(shù)后血壓是否下降無(wú)統(tǒng)計(jì)學(xué)相關(guān)性(P0.05)。梗阻時(shí)間大于3個(gè)月的患者術(shù)后血壓恢復(fù)率及血壓下降程度均低于梗阻時(shí)間小于3個(gè)月的患者,差異均有統(tǒng)計(jì)學(xué)意義(P0.05);中重度腎臟積水患者術(shù)后血壓恢復(fù)率及血壓下降程度均低于輕度腎積水患者,差異均有統(tǒng)計(jì)學(xué)意義(P0.05);PRA及AngⅡ值升高的患者術(shù)后血壓恢復(fù)率及血壓下降程度均低于PRA及AngⅡ值正常的患者,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。Logistic回歸多因素分析得出梗阻時(shí)間(OR=1.841)、腎臟積水程度(OR=2.997)、PRA及AngⅡ值(OR=3.931)是解除梗阻后高血壓持續(xù)的的危險(xiǎn)因素。結(jié)論:上尿路結(jié)石梗阻合并高血壓患者在解除梗阻后血壓可不同程度的恢復(fù)。梗阻時(shí)間3個(gè)月、腎臟中重度積水、PRA及AngⅡ值升高組患者術(shù)后收縮壓及舒張壓下降程度分別小于梗阻時(shí)間≤3個(gè)月、腎臟輕度積水、PRA及AngⅡ值正;颊。結(jié)石梗阻時(shí)間長(zhǎng)、腎臟積水程度重及AngⅡ及PRA值升高是上尿路結(jié)石梗阻合并高血壓患者解除梗阻后高血壓持續(xù)的危險(xiǎn)因素。
[Abstract]:Objective: to investigate the dynamic changes of blood pressure and its influencing factors in patients with upper urinary stone obstruction and hypertension, and to provide some theoretical and guiding basis for clinical treatment. Methods: from July 2014 to December 2016, 110 patients with upper urinary tract obstruction complicated with hypertension were treated in the affiliated Hospital of Zunyi Medical College. Sex, age, type of stone, operative method, time of obstruction, degree of hydronephrosis, distribution of stone, stone size, grade of hypertension, The effect of renin (PRA) and angiotensin 鈪,
本文編號(hào):2182059
[Abstract]:Objective: to investigate the dynamic changes of blood pressure and its influencing factors in patients with upper urinary stone obstruction and hypertension, and to provide some theoretical and guiding basis for clinical treatment. Methods: from July 2014 to December 2016, 110 patients with upper urinary tract obstruction complicated with hypertension were treated in the affiliated Hospital of Zunyi Medical College. Sex, age, type of stone, operative method, time of obstruction, degree of hydronephrosis, distribution of stone, stone size, grade of hypertension, The effect of renin (PRA) and angiotensin 鈪,
本文編號(hào):2182059
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