本文選題：尿路感染 + 尿腸球菌�。� 參考：《中國(guó)病原生物學(xué)雜志》2017年10期

【摘要】：目的研究尿路感染患者攜帶尿腸球菌流行病學(xué)及臨床特征,為尿路感染的診治提供指導(dǎo)。方法收集206例尿路感染患者臨床送檢尿液標(biāo)本,分離尿腸球菌,同一患者剔除重復(fù)株。采用VITEK32細(xì)菌檢測(cè)分析儀檢測(cè)菌落,并采用API板條鑒定菌種。藥敏試驗(yàn)采用K-B法,結(jié)果判定參照CLSI2016版。采用SPSS20.0軟件對(duì)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果檢出49例尿腸球菌感染者,≤44歲感染者12例,感染率18.46%;45~歲感染者17例,感染率24.64%;≥60歲感染者20例,感染率27.78%�！�44歲和44歲患者感染率差異無(wú)統(tǒng)計(jì)學(xué)意義(χ2=1.4853,P0.05);60歲和≥60歲患者感染率差異有統(tǒng)計(jì)學(xué)意義(χ2=0.9727,P0.05)。男性患者19例,感染率17.12%(19/111);女性患者30例,感染率31.58%(30/95);男、女患者感染率差異無(wú)統(tǒng)計(jì)學(xué)意義(χ2=5.9056,P0.05)。臨床表現(xiàn)以怕冷、發(fā)熱、腰痛等全身癥狀為主,且無(wú)癥狀性菌尿、尿路刺激、全身癥狀的患者分別有14、9和22例,感染率28.57%、18.37%和44.90%。實(shí)驗(yàn)室檢查中,白細(xì)胞、血沉、C反應(yīng)蛋白、降鈣素原、IgG、C3、肌酐值、胱蛋白酶抑制劑C、N-乙酰-β-D氨基葡萄糖苷酶、β2-微球蛋白、微量白蛋白以及內(nèi)毒素異常患者分別為24、9、8、3、7、8、7、8、28、22、29和20例,分別占48.97%、18.37%、16.33%、6.12%、14.29%、16.33%、14.29%、16.33%、57.14%、44.90%、59.18%和40.82%。49株尿腸球菌對(duì)諾氟沙星、慶大霉素、利福平、利奈唑胺、萬(wàn)古霉素、替考拉寧的耐藥率分別為61.22%、48.98%、32.65%、16.33%、0.00%和0.00%。結(jié)論尿腸球菌尿路感染以老年患者常見(jiàn),女性患者高發(fā),臨床表現(xiàn)以全身癥狀為主,實(shí)驗(yàn)室檢查以微量白蛋白和白細(xì)胞指標(biāo)異常為主要特征。尿腸球菌尿路感染治療可合理使用萬(wàn)古霉素和替考拉寧。
[Abstract]:Objective to study the epidemiology and clinical characteristics of enterococci carrying urinary tract infection in order to provide guidance for the diagnosis and treatment of urinary tract infection. Methods urine samples from 206 patients with urinary tract infection were collected and Enterococci were isolated and repeated strains were removed from the same patient. The colony was detected by VITEK32 bacterial analyzer, and the bacteria species were identified by API strip. The drug sensitivity test was performed by K-B method and the results were determined by CLSI2016. SPSS 20.0 software was used to analyze the data. Results there were 49 cases of enterococcus infection in urine, 12 cases of infection 鈮，

本文編號(hào)：2080767