本文選題：腹膜透析 + 頸動脈鈣化　； 參考：《重慶醫(yī)科大學學報》2017年02期

【摘要】：目的:探討維持性腹膜透析患者頸動脈鈣化的相關危險因素。方法:入選綿陽市中心醫(yī)院腹膜透析室穩(wěn)定接受規(guī)律腹膜透析的患者100人,按照頸動脈是否鈣化分為頸動脈鈣化組(55例),頸動脈正常組(45例)。收集患者臨床資料,評估殘余腎功能和透析充分性,采用彩超檢查評估頸動脈有無鈣化。用二元logistics回歸法分析頸動脈鈣化的獨立危險因素。結果:2組患者比較:頸動脈鈣化組較頸動脈正常組年齡(42.36±8.79 vs.34.93±9.60)歲、空腹血糖(6.91±0.44 vs.6.66±0.30)mmol/L、鈣磷乘積(3.98±0.40 vs.3.82±0.30)mmol/L、甲狀旁腺激素(parathyroid hormone,PTH)(270.72±30.24 vs.260.23±11.05)ng/L增加(P0.05),而殘余腎功能(2.25±0.74 vs.5.14±1.07)m L/min、總肌酐清除率(creatinine clearance rate,Ccr)(59.92±3.94 vs.66.11±7.01)L/(周·1.73 m~2)、殘余腎Ccr(19.66±2.85 vs.25.07±6.53)L/(周·1.73 m~2)、總尿素清除指數(urea clearance index,Kt/V)(4.06±0.51 vs.4.46±0.39)、殘腎Kt/V(1.12±0.30 vs.1.45±0.28)較頸動脈正常組降低(P0.05)。logistic回歸分析顯示:透析齡(OR=1.218,P=0.039)、鈣磷乘積(OR=70.403,P=0.037)、殘余腎功能(OR=0.030,P=0.001)、殘腎Ccr(OR=0.692,P=0.015)是頸動脈鈣化的影響因素。結論:行規(guī)律腹膜透析患者的頸動脈鈣化發(fā)生率較高,透析齡長、高鈣磷乘積和低殘余腎功能是腹膜透析患者發(fā)生頸動脈鈣化的獨立危險因素。
[Abstract]:Objective: to investigate the risk factors of carotid artery calcification in maintenance peritoneal dialysis patients. Methods: 100 patients who received regular peritoneal dialysis in peritoneal dialysis room of Mianyang central hospital were divided into carotid artery calcification group (55 cases) and normal carotid artery group (45 cases) according to whether the carotid artery was calcified or not. Clinical data were collected to evaluate residual renal function and dialysis adequacy, and carotid artery calcification was evaluated by color Doppler ultrasonography. The independent risk factors of carotid artery calcification were analyzed by binary logistics regression. Results the age of carotid calcification group was 42.36 鹵8.79 vs.34.93 鹵9.60 years old than that of normal carotid artery group. 絀鴻吂琛，

本文編號：2025800