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腎移植術后新發(fā)糖尿病:危險因素的回顧性分析

發(fā)布時間:2018-06-02 09:09

  本文選題:腎移植 + 糖尿病; 參考:《中國組織工程研究》2017年20期


【摘要】:背景:腎移植后代謝紊亂對預后的影響,尤其是新發(fā)糖尿病開始引起學者的重視。目的:了解腎移植術后新發(fā)糖尿病的危險因素,為識別腎移植術后新發(fā)糖尿病的高;颊,以及采取相應的預防措施提供參考依據(jù)。方法:回顧性病例分析365例同種異體腎移植患者的臨床資料,根據(jù)是否發(fā)生腎移植術后新發(fā)糖尿病,將患者分為腎移植術后新發(fā)糖尿病組(71例)和非腎移植術后新發(fā)糖尿病組(294例),采用單因素分析和非條件Logistic回歸分析腎移植術后新發(fā)糖尿病的獨立危險因素。結果與結論:(1)1年內腎移植術后新發(fā)糖尿病的累積發(fā)病率為19.45%;(2)非條件Logistic回歸中分析結果顯示,年齡≥45歲、體質量指數(shù)≥25 kg/m~2、糖尿病家族史、急性排斥反應是腎移植術后新發(fā)糖尿病發(fā)生的獨立危險因素;(3)結果提示,移植時年齡、糖尿病家族史、移植前體質量指數(shù)較高及移植后急性排斥反應的發(fā)生將會增加腎移植術后新發(fā)糖尿病的風險。
[Abstract]:Background: metabolic disorders after renal transplantation have a significant impact on prognosis, especially new diabetes mellitus. Objective: to investigate the risk factors of new diabetes mellitus after renal transplantation, and to provide reference for identifying high risk patients with new diabetes mellitus after renal transplantation and taking corresponding preventive measures. Methods: the clinical data of 365 patients with renal allograft transplantation were analyzed retrospectively. The patients were divided into two groups: renal transplantation group (n = 71) and non-renal transplantation group (n = 294). Univariate analysis and unconditioned Logistic regression analysis were used to analyze the independent risk factors of new diabetes mellitus after renal transplantation. Results and conclusion within 1 year, the cumulative incidence of new diabetes mellitus after renal transplantation was 19.4545 / 2) the age 鈮,

本文編號:1968218

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