發(fā)布時間：2018-05-22 20:15

  本文選題：前列腺癌 + 診斷��； 參考：《南昌大學(xué)》2014年碩士論文

【摘要】：目的： 回顧我院已追蹤隨訪134例前列腺癌患者的臨床資料，總結(jié)我科前列腺癌的診斷和治療現(xiàn)狀。 方法： 收集南昌大學(xué)第二附屬醫(yī)院自2008年8月至2013年8月收治的前列腺癌患者的臨床資料，并對臨床資料完整且能夠隨訪到的134例患者的臨床資料及隨訪資料進(jìn)行統(tǒng)計和分析，這些資料主要有患者的年齡、就診的主要原因、輔助檢查情況、臨床分期、病理分級、治療情況、治療后排尿及生存情況。 結(jié)果： 本組前列腺癌病例共有134例，年齡范圍為54~87歲，平均年齡72.4±4.4歲；因下尿路癥狀如排尿困難、尿頻、尿急、尿痛、血尿、尿潴留等癥狀就診有104例，占77.3%；血清PSA升高者124例，占92.5%；臨床分期C+D期占55.2%（74/134）；病理分級分化差或未分化的有66例，占82.5%（66/80）；行前列腺癌根治術(shù)的為15例，占11.2%，行手術(shù)去勢+比卡魯胺/氟他胺治療的有105例，占78.4%；行前列腺癌根治術(shù)的患者中有1例術(shù)后出現(xiàn)嚴(yán)重的尿失禁，行手術(shù)去勢+比卡魯胺/氟他胺治療的患者排尿情況絕大部分都有不同程度改善（102/105）；行手術(shù)去勢+比卡魯胺/氟他胺治療的105例患者中，死亡9例，死亡患者平均生存23.2個月。 結(jié)論： 前列腺癌就診患者多為高齡患者；就診的主要原因多為下尿路梗阻癥狀；就診時多為中晚期患者，病理分級多為分化差或未分化；PSA的對前列腺癌的敏感性較好，，目前PSA在前列腺癌的診斷中仍占據(jù)重要地位；內(nèi)分泌治療在國內(nèi)前列腺癌的治療中仍占有較高的比例，手術(shù)去勢聯(lián)合抗雄激素藥物治療患者的排尿癥狀都有不同程度的改善。
[Abstract]:Objective: The clinical data of 134 cases of prostate cancer in our hospital were reviewed, and the diagnosis and treatment of prostate cancer in our department were summarized. Methods: To collect the clinical data of patients with prostate cancer treated in the second affiliated Hospital of Nanchang University from August 2008 to August 2013, and to analyze the clinical data and follow-up data of 134 patients with complete clinical data, These data mainly include the patient's age, the main reason of seeing a doctor, auxiliary examination, clinical stage, pathological grading, treatment, urination and survival after treatment. Results: There were 134 cases of prostate cancer, with an average age of 72.4 鹵4.4 years, with an average age of 72.4 鹵4.4 years. 104 cases (77.3%) were treated for symptoms of lower urinary tract such as dysuria, frequency of urination, urgency, pain, hematuria, retention of urine, etc. 92.5%; clinical stage C D accounted for 55.2% / 134%; pathological grade was poor or undifferentiated in 66 cases (82.566 / 80%); radical prostatectomy was performed in 15 cases (11.2%); Ovariectomy was performed in 105 cases compared with Carous / flutamide. One of the patients undergoing radical prostatectomy had severe urinary incontinence after surgery. In most of the patients who underwent castration compared with Carous / flutamide, the urination status of the patients was improved to some extent, and 9 of the 105 patients treated with Carous / flutamide had died, and the average survival of the dead patients was 23.2 months. Conclusion: Most of the patients with prostate cancer were elderly patients, the main reason was lower urinary tract obstruction, most of them were middle or late stage patients, and the pathological grade was poor differentiation or undifferentiated PSA, and the sensitivity of prostate cancer was better. At present, PSA still plays an important role in the diagnosis of prostate cancer, endocrine therapy still occupies a high proportion in the treatment of prostate cancer in China, and the urination symptoms of patients treated with castration combined with anti-androgen drugs have been improved in varying degrees.
【學(xué)位授予單位】：南昌大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R737.25

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 祝宇,吳瑜璇,芮文斌,張烙

本文編號：1923459