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利用Nomogram模型預(yù)測中國人群的前列腺穿刺結(jié)果

發(fā)布時(shí)間:2018-05-21 19:46

  本文選題:前列腺穿刺 + PI-RADS; 參考:《浙江大學(xué)》2017年碩士論文


【摘要】:目的:以中國人群為基礎(chǔ)建立新的Nomogram模型預(yù)測前列腺穿刺的結(jié)果。方法:通過收集浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院2013年1月至2014年7月期間住院接受前列腺穿刺活檢的300名病人的信息。分別建立模型1和模型2,模型1的危險(xiǎn)因素包括:患者年齡、t-PSA值、f/t比值、前列腺體積(PV)和TRUS結(jié)果,模型2在模型1的基礎(chǔ)上加入前列腺磁共振PI-RADS評(píng)分。利用Nomogram比較模型1與模型2的差異。從而評(píng)估加入PI-RADS的新的Nomogram預(yù)測前列腺穿刺結(jié)果的效能。結(jié)果:模型1的c-值為0.883,模型2的c-值為0.893。兩個(gè)模型的內(nèi)部驗(yàn)證的尺度曲線與理想曲線相比,模型2較模型1也更加理想。另外,模型1與模型2的AUC分別是0.882和0.893,兩者有顯著性差異(p0.05)。結(jié)論:本文引入的新Nomogram模型,對(duì)今后中國人群的前列腺穿刺結(jié)果預(yù)測有一定的指導(dǎo)作用。
[Abstract]:Objective: to establish a new Nomogram model based on Chinese population to predict the outcome of prostate puncture. Methods: the data of 300 patients admitted to the first affiliated Hospital of Zhejiang University Medical College from January 2013 to July 2014 were collected. Model 1 and model 2 were established respectively. The risk factors of model 1 included: age of patients with t-PSA / f / t ratio, prostate volume and TRUS results. Model 2 added prostate magnetic resonance PI-RADS score on the basis of model 1. Nomogram was used to compare the difference between model 1 and model 2. To evaluate the efficacy of the new Nomogram with PI-RADS in predicting prostate puncture results. Results: the c- value of model 1 was 0.883, and that of model 2 was 0.893. Compared with ideal curve, model 2 is more ideal than model 1. In addition, the AUC of model 1 and model 2 were 0.882 and 0.893, respectively, there was significant difference between them (p 0.05). Conclusion: the new Nomogram model introduced in this paper can guide the prediction of prostate puncture results in Chinese population.
【學(xué)位授予單位】:浙江大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R737.25

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 蘆志華;朱生才;朱剛;馬宏;萬奔;王建業(yè);;經(jīng)會(huì)陰和經(jīng)直腸途徑前列腺穿刺活檢并發(fā)癥的比較分析[J];臨床泌尿外科雜志;2008年05期

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本文編號(hào):1920503

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