噻托溴銨吸入劑對合并慢阻肺的良性前列腺增生患者排尿障礙的影響
發(fā)布時間:2018-05-17 07:32
本文選題:肺疾病慢性阻塞性 + 噻托溴銨; 參考:《實用醫(yī)學(xué)雜志》2017年03期
【摘要】:目的:研究噻托溴銨吸入劑對合并慢阻肺的良性前列腺增生患者排尿障礙的影響。方法:前瞻性研究96例使用噻托溴銨吸入劑治療合并慢阻肺的良性前列腺增生患者為治療組,設(shè)25例未吸入制劑的患者為對照組,治療6個月后采用國際前列腺癥狀評分表(IPSS)、生活質(zhì)量量表(QOL)、最大尿流率(Q_(Max))、平均尿流率(Q_(ave))、達(dá)最大尿流率時間(TTQ_(Max))、殘余尿量(PVR)、膀胱排尿效率(BVE%)對患者進(jìn)行排尿障礙評價,所有患者均檢查肺功能、前列腺體積、前列腺特異性抗原(PSA)水平。結(jié)果:噻托溴銨吸入劑治療前、治療6個月和對照組比較,IPSS(15.1±4.1、16.3±3.4和14.7±3.1,P=0.864);QOL(3.9±0.8、4.0±0.8和4.0±0.9,P=0.992);Q_(Max)(ml/s)(8.5±2.9、10.9±2.2和9.0±2.4,P=0.214);Qave(ml/s)(3.9±1.2、5.0±1.4和3.8±0.9,P=0.054);TTQ_(Max)(s)(11.1±5.6、11.2±4.0和10.4±5.1,P=0.424);PVR(mL)(56.8±33.3、62.3±30.5和57.4±29.5,P=0.981);BVE(%)(75.6±13.8、72.7±10.5和74.3±12.1,P=0.992),以上均差異無統(tǒng)計學(xué)意義。結(jié)論:噻托溴銨吸入劑不引起合并慢阻肺的良性前列腺增生患者發(fā)生排尿障礙。
[Abstract]:Aim: to study the effect of tiotropium bromide inhalation on dysuria in patients with benign prostatic hyperplasia (BPH) complicated with chronic obstructive pulmonary disease (COPD). Methods: in a prospective study, 96 patients with benign prostatic hyperplasia with chronic obstructive pulmonary disease were treated with tiotropium bromide inhalation as the treatment group, and 25 patients without inhaled preparations as the control group. After 6 months of treatment, the patients were evaluated with IPSS scale, quality of life scale (QOLL), maximum urinary flow rate (MVF), QV Maxtix, average uroflow rate (UF), maximum urinary flow time (TTV), residual urine volume (PVR) and bladder urination efficiency (BVEI). All patients were examined for lung function, prostate volume and prostate specific antigen (PSA) level. 緇撴灉:鍣繪墭婧撮摰鍚稿叆鍓傛不鐤楀墠,娌葷枟6涓湀鍜屽鐓х粍姣旇緝,IPSS(15.1鹵4.1,16.3鹵3.4鍜,
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