本文選題：精索靜脈曲張 + 程度　； 參考：《新疆醫(yī)科大學》2017年碩士論文

【摘要】：目的:研究不同程度的精索靜脈曲張(VC)臨床表現(xiàn)與性激素變化的相關性及其特征,提出臨床工作中對精索靜脈曲張(VC)治療的建議。方法:從2015年3月—2016年9月在門診就診的患者中,查體有精索靜脈曲張表現(xiàn)、彩超證實有精索靜脈形態(tài)學改變,根據(jù)兩者可明確診斷為精索靜脈曲張(VC),同時根據(jù)程度不同按照診斷標準將精索靜曲張患者分為3個亞組(其中雙側(cè)精索靜脈曲張時以較重側(cè)為主),按照隨機數(shù)字表法在各亞組中選取30例患者。我院泌尿科作為婚檢定點醫(yī)院,在同期體檢的健康人群中按上述方法選取30例。對其外周血中卵泡刺激素(FSH)、黃體生成素(LH)和睪酮(T)水平測定,并進行比較觀察。對各組患者進行臨床表現(xiàn)問卷調(diào)查,根據(jù)VC患者臨床表現(xiàn)分度表,對3組患者臨床癥狀進行對比觀察。結(jié)果:各病例組的血清FSH和LH水平均較對照組升高(P0.05),不同程度VC患者間FSH、LH間兩兩相比,得出F=7.38(P0.05),F=9.23(P0.05),結(jié)果差異有統(tǒng)計學意義,可以認為不同程度精索靜脈曲張的FSH、LH水平不全相同;T水平在各組中較對照組均未見明顯降低(P0.05),而每組之間進行比較,得出F=0.59(P0.05),結(jié)果無統(tǒng)計學意義,可以認為不同程度精索靜脈曲張的T水平變化不大。在各病例組臨床癥狀之間比較,得出?(17)(28)(18)(15)(13)(16)(20)(P0.05),結(jié)果差異有統(tǒng)計學意義,可以認為不同程度精索靜脈曲張的臨床表現(xiàn)不全相同,并且臨床表現(xiàn)隨著精索靜脈曲張程度的加重而加重。結(jié)論:VC可引起患者外周血FSH、LH水平升高,說明VC對男性性激素確實有一定影響,并隨不同程度精索靜脈曲張而變化;VC患者的外周血T水平變化不顯著,可能VC對睪丸的損害程度與臨床程度無關;VC患者臨床癥狀中表現(xiàn)來看,精索靜脈曲張的臨床表現(xiàn)隨著精索靜脈曲張程度的加重而加重,根據(jù)這一結(jié)論可以對精索靜脈曲張治療提出建議。
[Abstract]:Objective: to study the relationship between the clinical manifestations of varicocele and the changes of sex hormones, and to put forward some suggestions for the treatment of varicocele. Methods: from March 2015 to September 2016, patients with varicocele were examined, and morphological changes of spermatic veins were confirmed by color Doppler ultrasonography. The patients with varicocele can be definitely diagnosed as varicocele according to the degree of varicocele, and the patients with varicocele are divided into three subgroups according to the diagnostic criteria. The patients with varicocele in bilateral varicocele are divided into three subgroups. 30 patients in each subgroup were selected by tabular method. The urology department of our hospital, as a designated hospital for premarital examination, selected 30 cases according to the above method in the same period of physical examination of the healthy population. The levels of follicle stimulating hormone (FSH), luteinizing hormone (LH) and testosterone (T) in peripheral blood were measured and compared. The clinical symptoms of the three groups were compared and observed according to the clinical manifestation scale of VC patients. Results: the serum levels of FSH and LH in each case group were higher than those in the control group (P 0.05). The results showed that the serum levels of FSH and LH in patients with different degrees of VC were significantly higher than those in the control group. The results showed that the serum levels of FSH and LH in each group were significantly higher than those in the control group. It can be concluded that the levels of FSHL LH in varicocele of different degrees are not the same as those in the control group. The results showed that there was no significant difference in the level of FSH LH between each group and the control group, and the results were not statistically significant. The T level of varicocele with different degrees of varicocele may be considered to have little change. The clinical symptoms of each group were compared, and it was concluded that the clinical manifestations of varicocele of different degrees were different, and the clinical manifestations were aggravated with the exacerbation of varicocele. Conclusion the level of FSH LH in peripheral blood of patients with VC can be increased by 1: VC, which indicates that VC does have a certain effect on male sex hormone, and the changes of T level in peripheral blood of patients with VC with different degrees of varicocele are not significant. It is possible that the degree of testicular damage caused by VC is not related to the clinical degree. The clinical manifestation of varicocele is aggravated with the severity of varicocele. According to this conclusion, the treatment of varicocele can be recommended.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R697.24

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