本文關鍵詞：現(xiàn)行結(jié)核菌檢測技術應用于泌尿系統(tǒng)結(jié)核診斷的研究進展，由筆耕文化傳播整理發(fā)布。

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現(xiàn)行結(jié)核菌檢測技術應用于泌尿系統(tǒng)結(jié)核診斷的研究進展 何莎，周偉，張五星

100091 北京，解放軍第309醫(yī)院全軍器官移植研究所腎臟病科
周偉，Email: snowpromise2012@163.com

摘要:泌尿系統(tǒng)結(jié)核居于肺外結(jié)核第三位，其中最主要的是腎結(jié)核。腎結(jié)核是由結(jié)核分枝桿菌引起的慢性、進行性、破壞性病變，常因其結(jié)核癥狀不典型致使臨床診療上易漏診誤診，從而延誤治療時機，給患者泌尿系統(tǒng)帶來很大損傷。目前泌尿系統(tǒng)結(jié)核的確診主要依賴于臨床表現(xiàn)結(jié)合實驗室檢查、影像學檢查等。但是橫跨在現(xiàn)有技術與泌尿系統(tǒng)結(jié)核臨床診斷需要之間的鴻溝依舊為其早期診斷、病情評估和預后監(jiān)測帶來了不可避免的影響，這也阻礙了泌尿系統(tǒng)結(jié)核診斷方式更新的探索與發(fā)展。伴隨著納米技術和微流體技術的飛速發(fā)展，很多檢測結(jié)核分枝桿菌的生物傳感器應運而生。近年來納米/微流體技術已經(jīng)被廣泛應用于發(fā)展現(xiàn)場檢測多種疾病的診斷和監(jiān)測技術方面，這預示著在結(jié)核病診斷方面應用納米/微流體技術也是不可避免的趨勢，更為診斷泌尿系統(tǒng)結(jié)核尋找更為可靠準確的依據(jù)和方法提供了新的契機。以下對泌尿系統(tǒng)結(jié)核的臨床表現(xiàn)、診斷方法、橫跨在現(xiàn)有技術與泌尿系統(tǒng)結(jié)核臨床診斷之間的鴻溝、結(jié)核病診斷的納米/微流體技術以及納米/微流體技術能否為泌尿系統(tǒng)結(jié)核診斷與監(jiān)測提供未來前景等方面進行綜述。

關鍵詞:結(jié)核，泌尿生殖系統(tǒng); 分枝桿菌，，結(jié)核; 檢測方法; 納米/微流體技術

Research progress on the application of the current tuberculosis detection technology in the diagnosis of urinary tuberculosis He Sha, Zhou Wei, Zhang Wuxing

Department of Nephropathy, Organ Transplant Research Institute, the 309th Hospital of PLA, Beijing 100091, China
Zhou Wei, Email: snowpromise2012@163.com

Abstract:Tuberculosis of urinary system is third of the extra pulmonary tuberculosis, because of its atypical clinical symptoms of tuberculosis caused easily misdiagnosed, thus delay treatment timing, for patients with urinary system bring great damage. At present, the diagnosis of urinary system tuberculosis mainly depends on the clinical manifestations with laboratory examination and imaging examination. But across the gap of existing technology and clinical diagnosis of tuberculosis of urinary system between the needs still brings the inevitable effect on early diagnosis, condition assessment and prognosis. It also impedes the update tuberculosis diagnosis way of urinary system. With the rapid development of the nanotechnology/microfluidics, biosensors for the detection of Mycobacterium tuberculosis emerge as the times. In recent years, nanotechnology/microfluidics has already been widely applied to the detection of various diseases at point of care. This indicates the inevitable trend of the application of nanotechnology/microfluidics in the diagnosis of tuberculosis, also provides a new opportunity for looking for more reliable and accurate basis and methods about tuberculosis of urinary system diagnosis. Hence introduced the clinical manifestations of tuberculosis of urinary system, the diagnosis of urinary system tuberculosis, the gap between existing technology, clinical diagnosis of tuberculosis of urinary system, and the diagnosis of tuberculosis in nanotechnology/microfluidics and they can provide the future prospects for the diagnosis of urinary tuberculosis detection.

Keywords:Tuberculosis, urogenital; Mycobacterium tuberculosis; Detection method; Nanotechnology/microfluidics

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(編輯：戚紅丹 收稿日期：2014-09-28)

  本文關鍵詞：現(xiàn)行結(jié)核菌檢測技術應用于泌尿系統(tǒng)結(jié)核診斷的研究進展，由筆耕文化傳播整理發(fā)布。

本文編號：163665