老年腦梗死泌尿系感染患者白介素與組織因子的變化研究
發(fā)布時(shí)間:2018-03-16 04:23
本文選題:老年腦梗死 切入點(diǎn):泌尿系感染 出處:《中華醫(yī)院感染學(xué)雜志》2016年15期 論文類(lèi)型:期刊論文
【摘要】:目的研究老年腦梗死合并泌尿系感染患者血清及尿液白介素(IL)及組織因子的變化,為該類(lèi)老年患者泌尿系感染的預(yù)防和治療提供參考依據(jù)。方法選取2014年5月-2015年9月醫(yī)院60例老年腦梗死合并泌尿系感染患者為觀(guān)察組,同期選取60例老年腦梗死患者為對(duì)照組,比較兩組患者的血清及尿液白介素及組織因子水平,數(shù)據(jù)采用SAS 6.0軟件進(jìn)行統(tǒng)計(jì)分析。結(jié)果觀(guān)察組血清及尿液IL-1β、IL-6、IL-8、IL-10及TF水平分別為(3.45±0.42)(16.36±1.89)(18.52±2.20)(28.98±3.04)pg/ml及(1.64±0.21)U/L,均高于對(duì)照組,且觀(guān)察組不同感染程度及感染部位者血清及尿液檢測(cè)結(jié)果差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論老年腦梗死合并泌尿系感染患者血清及尿液白介素及組織因子呈現(xiàn)高表達(dá)狀態(tài),不同感染程度及感染部位者的血清及尿液檢測(cè)結(jié)果也存在明顯差異,應(yīng)給予充分的重視及干預(yù)。
[Abstract]:Objective to study the changes of serum and urine interleukin (IL) and tissue factors in elderly patients with cerebral infarction complicated with urinary tract infection. Methods from May 2014 to September 2015, 60 elderly patients with cerebral infarction complicated with urinary tract infection were selected as the observation group. In the same period, 60 elderly patients with cerebral infarction were selected as control group. The levels of serum and urine interleukin and tissue factors were compared between the two groups. Results the levels of IL-8 / IL-10 and TF in serum and urine of the observation group were 3.45 鹵0.42U / L and 18.52 鹵2.20g / ml and 1.64 鹵0.21U / L, respectively, which were significantly higher than those in the control group, the data were analyzed by SAS 6.0 software, and the results showed that the levels of IL-10 and TF in serum and urine in the observation group were higher than those in the control group, respectively, and the levels of IL-10 and TF in serum and urine were higher than those in the control group. There were significant differences in serum and urine in patients with different infection degree and infection site. Conclusion Serum and urine interleukin and tissue factors in elderly patients with cerebral infarction complicated with urinary tract infection are highly expressed. There were significant differences in serum and urine of patients with different infection degree and infection site, which should be paid more attention and intervention.
【作者單位】: 許昌市中心醫(yī)院神經(jīng)外科;
【基金】:河南省科技廳基金資助項(xiàng)目(201348907G)
【分類(lèi)號(hào)】:R743.3;R691.3
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本文編號(hào):1618318
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