發(fā)布時(shí)間：2018-03-13 02:35

  本文選題：.%氯化鈉溶液(鹽水)　切入點(diǎn)：高氯血癥　出處：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2016年03期 　論文類型：期刊論文

【摘要】：本文旨在客觀評(píng)價(jià)0.9%氯化鈉溶液(鹽水)的生物化學(xué)和病理生理學(xué)特性,并深入探討靜脈輸注該鹽水對(duì)機(jī)體酸堿平衡和腎臟血流動(dòng)力學(xué)的影響。研究表明多數(shù)臨床醫(yī)生對(duì)電解質(zhì)平衡的認(rèn)識(shí)有限,對(duì)靜脈輸注鹽水所引起的血漿電解質(zhì)變化認(rèn)識(shí)不足。而錯(cuò)誤地應(yīng)用鹽水會(huì)增加患者的患病率和死亡率。健康成人大劑量(2L)輸注鹽水會(huì)導(dǎo)致高氯血癥并進(jìn)而引起代謝性酸中毒、高鉀血癥和負(fù)氮平衡�？傊�,鹽水是一種高度酸化的液體,用于治療嘔吐或上消化道減壓引起的低氯性代謝性堿中毒和容量不足較為合適。臨床上不加區(qū)分地應(yīng)用鹽水對(duì)患者特別是對(duì)重癥患者可能導(dǎo)致不必要的并發(fā)癥,應(yīng)注意避免。臨床醫(yī)生對(duì)于鹽水相關(guān)作用和電解質(zhì)管理的認(rèn)識(shí)亟需增強(qiáng)。
[Abstract]:The objective of this paper is to evaluate the biochemical and pathophysiological properties of 0.9% sodium chloride solution (brine). The effects of intravenous infusion of the saline on the balance of acid and base and renal hemodynamics were also studied. The results showed that most clinicians had limited knowledge of electrolyte balance. There is a lack of understanding of the changes in plasma electrolytes caused by intravenous saltwater infusion. However, the wrong use of salt water increases the morbidity and mortality of patients. The saline infusion of healthy adults can lead to hyperchloremia and, in turn, metabolic acidosis. Hyperkalemia and negative nitrogen balance. In short, brine is a highly acidified liquid, Low chlorine metabolic alkalosis and insufficient volume due to vomiting or upper gastrointestinal decompression are more appropriate. Clinical use of saline without distinction may lead to unnecessary complications in patients, especially in severe cases, Attention should be paid to avoid. Clinicians' understanding of brine-related roles and electrolyte management needs to be enhanced.
【作者單位】： Kidney
【基金】：support of the ISN Sister Renal Center Program
【分類號(hào)】：R692

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本文編號(hào)：1604452