本文關(guān)鍵詞：前列腺基底細(xì)胞癌3例　出處：《北京大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2016年04期 　論文類(lèi)型：期刊論文

  更多相關(guān)文章： 癌 基底細(xì)胞 癌 腺樣囊性 前列腺腫瘤

【摘要】：探討前列腺基底細(xì)胞癌(basal cell carcinoma,BCC)臨床病理特點(diǎn)并提高診療認(rèn)識(shí)。通過(guò)報(bào)道3例BCC患者的臨床病理特點(diǎn)及診療經(jīng)過(guò),結(jié)合文獻(xiàn)復(fù)習(xí),提高對(duì)BCC診療特點(diǎn)的認(rèn)識(shí)。3例BCC患者年齡為57~83歲,其中1例因血尿就診,2例因排尿困難就診。3例患者均合并前列腺增生,其中2例患者前列腺特異性抗原(prostate specific antigen,PSA)增高,1例PSA正常。病例1前列腺癌侵及膀胱、直腸前筋膜,伴淋巴結(jié)轉(zhuǎn)移、骨轉(zhuǎn)移、雙肺多發(fā)轉(zhuǎn)移,2014年11月2日行膀胱全切+雙側(cè)輸尿管皮膚造口術(shù)+雙側(cè)閉孔及髂內(nèi)淋巴結(jié)清掃術(shù),術(shù)后病理診斷BCC,2015年1月8日復(fù)查盆腔增強(qiáng)MRI提示盆腔內(nèi)復(fù)發(fā),2015年7月11日復(fù)查腹部增強(qiáng)CT提示肝多發(fā)轉(zhuǎn)移,胰腺轉(zhuǎn)移,2015年10月因前列腺癌死亡。病例2于2015年3月27日行前列腺穿刺病理診斷為BCC,伴肺轉(zhuǎn)移及骨轉(zhuǎn)移,行化療及內(nèi)分泌治療,后行局部放射治療,2016年1月11日復(fù)查正電子發(fā)射斷層顯像與計(jì)算機(jī)斷層顯像(positron emission tomography and computed tomography,PET-CT)示患者肺轉(zhuǎn)移瘤及骨轉(zhuǎn)移瘤直徑較前增大,數(shù)量增多,隨訪至2016年1月10日患者帶瘤生存。病例3外院行經(jīng)尿道前列腺電切術(shù)(transurethral resection of prostate,TURP),術(shù)后病理考慮BCC可能,行PET-CT提示殘余前列腺惡性腫瘤,伴雙側(cè)盆腔淋巴結(jié)轉(zhuǎn)移可能,2016年4月20日復(fù)查PET-CT提示盆腔可見(jiàn)巨大不規(guī)則混雜密度影,臨床考慮腫瘤復(fù)發(fā),遂予局部放射治療,隨訪至2016年1月10日患者帶瘤生存。BCC臨床罕見(jiàn),是一種侵襲能力強(qiáng)、惡性程度較高、易發(fā)生轉(zhuǎn)移的腫瘤,需要給予積極的治療和密切的隨訪。
[Abstract]:To investigate the basal cell carcinoma of basal cell carcinoma of the prostate. The clinicopathological characteristics and diagnosis and treatment of 3 cases of BCC were reported and reviewed in combination with literature review. The age of 3 BCC patients was 57 ~ 83 years old. One patient with hematuria and 2 patients with dysuria were all complicated with prostatic hyperplasia. Among them, 2 patients with prostate specific antigen specific antigen-PSAs increased in 1 case, PSA was normal in 1 case, and prostate cancer invaded bladder in case 1. Rectal anterior fascia, with lymph node metastasis, bone metastasis, multiple metastasis of both lungs. In November 2nd 2014, total cystectomy and bilateral ureterostomy were performed with bilateral obturator and internal iliac lymph node dissection. Postoperative pathological diagnosis of BCC, pelvic enhanced MRI on January 8th 2015 to indicate pelvic recurrence, abdominal CT on July 11th 2015 to indicate multiple liver metastasis, pancreatic metastasis. Case 2 died of prostate cancer on October 2015. Case 2 was diagnosed as BCC with lung metastasis and bone metastasis on March 27th 2015, and received chemotherapy and endocrine therapy. Then local radiotherapy was performed. In January 11th 2016, positron emission tomography and computed tomography (. Positron emission tomography and computed tomography. PET-CTS showed that the diameter and number of pulmonary metastases and bone metastases were larger and larger. Case 3 patients underwent transurethral resection of the prostate (TURP). Transurethral resection of prostate. TURP, BCC may be considered pathologically after operation, PET-CT suggests residual benign prostate neoplasms with bilateral pelvic lymph node metastasis. In April 20th 2016, PET-CT showed that large irregular mixed density could be seen in the pelvic cavity, and the recurrence of the tumor was considered clinically, and then local radiotherapy was given. Follow-up to January 10th 2016 patients with tumor survival. BCC clinical rare, is a strong invasive, high degree of malignancy, prone to metastasis, need to be actively treated and closely followed up.
【作者單位】： 北京大學(xué)第三醫(yī)院泌尿外科;北京大學(xué)第三醫(yī)院病理科;北京大學(xué)第一醫(yī)院泌尿外科;
【分類(lèi)號(hào)】：R737.25
【正文快照】： 醫(yī)院泌尿外科,北京100034)△Corresponding author’s e-mail,malulin@medmail.com.cnThen the patient received local radiation therapy.The patient survived in the followed upon January 10,2016.BCC of prostate is a rare subtype.Due to the local infiltrative and

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 付長(zhǎng)霞;薛德彬;張仁亞;;前列腺基底細(xì)胞癌:29例臨床病理分析[J];臨床與實(shí)驗(yàn)病理學(xué)雜志;2007年06期

2 肖立,陸孝禹;前列腺基底細(xì)胞增生的形態(tài)學(xué)觀察[J];老年醫(yī)學(xué)與保健;2003年02期

3 周彥;劉定益;唐崎;王健;;前列腺基底細(xì)胞癌一例報(bào)告及文獻(xiàn)復(fù)習(xí)[J];中華泌尿外科雜志;2006年06期

4 申麗;姚敏;劉強(qiáng);;前列腺基底細(xì)胞癌1例報(bào)道[J];診斷病理學(xué)雜志;2006年05期

5 嚴(yán)澤軍;謝國(guó)海;蔣軍輝;沈志久;程躍;;前列腺基底細(xì)胞癌一例報(bào)告并文獻(xiàn)復(fù)習(xí)[J];現(xiàn)代實(shí)用醫(yī)學(xué);2009年11期

6 劉健紅;吳云飛;金曙蕾;喬曼莉;;前列腺基底細(xì)胞腫瘤一例臨床病理特征分析[J];海南醫(yī)學(xué);2010年17期

7 李君貴;姜山;高興林;;前列腺基底細(xì)胞癌1例[J];臨床泌尿外科雜志;2012年01期

8 楊華;前列腺基底細(xì)胞增生[J];中華病理學(xué)雜志;1998年06期

9 彭杰青,余俐,暴菊英,周瑩;26例前列腺基底細(xì)胞增生及腫瘤的形態(tài)學(xué)和免疫組化觀察[J];中華老年醫(yī)學(xué)雜志;1998年05期

10 楊華,HaiyenEZhau,HenryFrieson,LelandWKChkng;前列腺基底細(xì)胞增生的診斷與鑒別[J];白求恩醫(yī)科大學(xué)學(xué)報(bào);1999年06期

相關(guān)會(huì)議論文 前5條

1 嚴(yán)澤軍;程躍;沈志久;王國(guó)耀;袁鶴勝;蔣軍輝;李和明;蔣照輝;謝國(guó)海;;前列腺基底細(xì)胞癌一例報(bào)告并文獻(xiàn)復(fù)習(xí)[A];2009年浙江省男科、泌尿外科學(xué)術(shù)年會(huì)論文匯編[C];2009年

2 楊為民;嚴(yán)澤軍;陳志強(qiáng);藍(lán)儒竹;劉繼紅;葉章群;;前列腺基底細(xì)胞癌一例報(bào)告并文獻(xiàn)復(fù)習(xí)[A];湘鄂贛首屆性與生殖健康學(xué)術(shù)研討會(huì)論文匯編[C];2007年

3 宋日進(jìn);華立新;殷長(zhǎng)軍;宋寧宏;孟小鑫;張杰秀;呂強(qiáng);李杰;張煒;徐正銓;眭元庚;;前列腺基底細(xì)胞癌3例報(bào)告及文獻(xiàn)復(fù)習(xí)[A];第十五屆全國(guó)泌尿外科學(xué)術(shù)會(huì)議論文集[C];2008年

4 王功偉;沈丹華;;前列腺基底細(xì)胞病變[A];中華醫(yī)學(xué)會(huì)病理學(xué)分會(huì)2009年學(xué)術(shù)年會(huì)論文匯編[C];2009年

5 張祖平;張喬安;;介紹一種提高前列腺基底細(xì)胞檢測(cè)敏感性的方法[A];2010年中國(guó)藥學(xué)大會(huì)暨第十屆中國(guó)藥師周論文集[C];2010年

，

本文編號(hào)：1366513