【摘要】：目的：分析子宮富于細(xì)胞型平滑肌瘤的臨床特征、病理特點(diǎn),探討其生物學(xué)行為及臨床結(jié)局,以達(dá)到對(duì)疾病更全面的認(rèn)識(shí),避免過(guò)度治療或治療不足。 方法：選取昆明醫(yī)科大學(xué)第一附屬醫(yī)院婦科2013年1月～2013年12月間收治行手術(shù)治療后病理診斷為子宮肌瘤的495例患者臨床資料。富于細(xì)胞型平滑肌瘤150例納入研究組,子宮平滑肌瘤100例納入對(duì)照組。排出其他特殊類(lèi)型的子宮肌瘤或子宮肉瘤245例。就其發(fā)病年齡、發(fā)病率、臨床特征、病理特點(diǎn)、治療方案及預(yù)后等方面進(jìn)行回顧性分析研究。 結(jié)果：子宮富于細(xì)胞型平滑肌瘤發(fā)病年齡、臨床特征、影像學(xué)檢查、治療方案、住院時(shí)間等與普通型平滑肌瘤相比,除痛經(jīng)、貧血、B超提示部分高回聲包塊外均無(wú)顯著性差異(P0.05)。術(shù)后隨訪130例,均存活,無(wú)一例復(fù)發(fā)、轉(zhuǎn)移,預(yù)后良好。 結(jié)論：子宮富于細(xì)胞型平滑肌瘤是一種特殊類(lèi)型的子宮肌瘤,病理組織學(xué)屬良性腫瘤。因鏡下細(xì)胞可異常豐富,甚至出現(xiàn)個(gè)別異型細(xì)胞,應(yīng)與平滑肌肉瘤相鑒別。手術(shù)治療可取得較好療效。但相關(guān)文獻(xiàn)報(bào)道,有晚期復(fù)發(fā)、轉(zhuǎn)移的可能,甚至有復(fù)發(fā)后診斷為低度惡性平滑肌肉瘤的病例,因此術(shù)后診斷為子宮富于細(xì)胞型平滑肌瘤的患者應(yīng)加強(qiáng)術(shù)后隨訪。
[Abstract]:Objective: to analyze the clinical and pathological characteristics of uterine cell-rich leiomyoma, and to explore its biological behavior and clinical outcome, so as to achieve a more comprehensive understanding of the disease and avoid excessive treatment or insufficient treatment. Methods: the clinical data of 495 patients with uterine myoma diagnosed pathologically from January 2013 to December 2013 in the first affiliated Hospital of Kunming Medical University were selected. 150 cases of cell-rich leiomyoma and 100 cases of uterine leiomyoma were included in the study group. 245 cases of other special types of uterine myoma or uterine sarcomas were excreted. The age of onset, incidence, clinical characteristics, pathological characteristics, treatment scheme and prognosis were analyzed and studied retrospectively. the age of onset, incidence, clinical characteristics, pathological characteristics, treatment scheme and prognosis were analyzed retrospectively. Results: there were no significant differences in age, clinical features, imaging examination, treatment scheme and hospitalization time between uterine cell-rich leiomyoma and common leiomyoma, except dysmenorrhea, anemia and B-ultrasound. 130 cases were followed up, all of them survived, no recurrence, metastasis and good prognosis. Conclusion: uterine cell-rich leiomyoma is a special type of uterine myoma, which belongs to benign tumor in pathology. Because of the abnormal abundance of cells and even the appearance of individual heterogeneic cells, it should be distinguished from leiomyosarcoma. Surgical treatment can achieve good results. However, it is reported that there is the possibility of late recurrence and metastasis, and even cases of low grade malignant leiomyosarcoma diagnosed after recurrence, so patients diagnosed as uterine cell-rich leiomyoma after operation should be followed up.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類(lèi)號(hào)】：R737.33

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本文編號(hào)：2509097