【摘要】：目的：觀察研究宮腹腔鏡術(shù)后口服助孕Ⅱ號(hào)方治療輸卵管阻塞性不孕患者的臨床療效。 方法：將符合篩選標(biāo)準(zhǔn)的60例患者，采用隨機(jī)數(shù)字法分為治療組和對(duì)照組，每組30例，在進(jìn)行宮腹腔鏡手術(shù)后常規(guī)抗感染治療以外，治療組給予口服助孕Ⅱ號(hào)方治療，對(duì)照組采取期待療法。 結(jié)果： ①宮內(nèi)妊娠情況比較：治療組宮內(nèi)妊娠12例，對(duì)照組宮內(nèi)妊娠5例，治療組療效優(yōu)于對(duì)照組（P＜0.05）； ②未受孕者術(shù)后1年輸卵管通暢情況比較：治療組通暢率55.56%，堵塞率30.56%，對(duì)照組通暢率26.00%，，堵塞率50.00%，治療組優(yōu)于對(duì)照組（P＜0.05）； ③治療前后的癥狀體征積分情況比較：治療組治療前的總積分平均22.80±7.13，治療后的總積分平均7.77±5.16，對(duì)照組治療前的總積分平均22.40±6.94，治療后的總積分平均10.93±7.13，兩組的治療都可以緩解患者的臨床癥狀、體征（P＜0.05），但是兩組治療后的總積分經(jīng)檢驗(yàn)無(wú)明顯差異（P＞0.05）； ④綜合療效情況比較：治療組30例中治愈12例，顯效6例，有效11例，無(wú)效1例，總有效率96.67%，對(duì)照組30例中治愈5例，顯效4例，有效13例，無(wú)效8例，總有效率73.33%，治療組療效優(yōu)于對(duì)照組（P＜0.05）； ⑤病情嚴(yán)重程度與宮內(nèi)妊娠情況比較：16例輕度患者中有9例（56.25%）宮內(nèi)妊娠，33例中度患者中有7例（21.21%）宮內(nèi)妊娠，11例重度患者中有1例（9.09%）宮內(nèi)妊娠，病情程度越輕，宮內(nèi)妊娠率越高（P＜0.05）； ⑥術(shù)后妊娠時(shí)間比較：治療組6—12個(gè)月內(nèi)宮內(nèi)妊娠6例，對(duì)照組6—12個(gè)月內(nèi)宮內(nèi)妊娠1例，治療組優(yōu)于對(duì)照組（P＜0.05）。結(jié)論：宮腹腔鏡術(shù)后結(jié)合助孕Ⅱ號(hào)方治療輸卵管阻塞性不孕有一定的臨床療效，沒(méi)有明顯不良反應(yīng)，可提高患者宮內(nèi)妊娠率，防止輸卵管再粘連的發(fā)生。
[Abstract]:Objective: to observe and study the clinical effect of oral Zhiyao No. 2 recipe after hysteroscopy in the treatment of infertile patients with tubal obstruction. Methods: sixty patients who met the screening criteria were randomly divided into treatment group (n = 30) and control group (n = 30). In addition to routine anti-infection treatment after laparoscopic hysteroscopy, the treatment group was treated with oral Zhuyue recipe II. The control group was treated with expectation therapy. Results: 1 comparison of intrauterine pregnancy: there were 12 cases of intrauterine pregnancy in the treatment group and 5 cases in the control group. The curative effect of the treatment group was better than that of the control group (P < 0.05). 2 comparison of tubal patency in patients without pregnancy one year after operation: the patency rate of the treatment group was 55.56%, the blocking rate was 30.56%, the patency rate of the control group was 26.00%, and the blocking rate was 50.00%. The treatment group was superior to the control group (P < 0.05). 3Compared with the scores of symptoms and signs before and after treatment: the average total score was 22.80 鹵7.13 in the treatment group, 7.77 鹵5.16 in the treatment group and 22.40 鹵6.94 in the control group before treatment. The average total score after treatment was 10.93 鹵7.13. Both groups could relieve the clinical symptoms and signs (P < 0.05), but there was no significant difference in the total score between the two groups (P > 0.05). 4 comparison of comprehensive curative effects: in the treatment group, 12 cases were cured, 6 cases were markedly effective, 11 cases were effective, 1 case was ineffective, the total effective rate was 96.67%, 5 cases were cured, 4 cases were markedly effective, 13 cases were effective and 8 cases were ineffective in the control group. The total effective rate was 73.33%. The curative effect of the treatment group was better than that of the control group (P < 0.05). (5) the severity of the disease was compared with that of intrauterine pregnancy: among 16 cases of mild pregnancy, 9 cases (56.25%) were pregnant in uterus, 7 cases (21.21%) in 33 cases were moderate, and there were 9 cases (56.25%) in mild cases and 7 cases (21.21%) in 33 cases. In 11 patients with severe pregnancy, 1 case (9.09%) was pregnant in uterus. The lighter the severity of the disease, the higher the rate of intrauterine pregnancy (P < 0.05). 6 comparison of postoperative pregnancy time: 6 cases of intrauterine pregnancy in the treatment group and 1 case in the control group within 6 times 12 months, the treatment group was better than the control group (P < 0.05). Conclusion: hysteroscopy combined with No. 2 prescription has certain clinical effect in the treatment of tubal obstructive sterility, and there is no obvious adverse reaction, which can improve the rate of intrauterine pregnancy and prevent the recurrence of tubal adhesion.
【學(xué)位授予單位】：云南中醫(yī)學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類(lèi)號(hào)】：R711.6

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