【摘要】：目的：觀察研究宮腹腔鏡術后口服助孕Ⅱ號方治療輸卵管阻塞性不孕患者的臨床療效。 方法：將符合篩選標準的60例患者，采用隨機數字法分為治療組和對照組，每組30例，在進行宮腹腔鏡手術后常規(guī)抗感染治療以外，治療組給予口服助孕Ⅱ號方治療，對照組采取期待療法。 結果： ①宮內妊娠情況比較：治療組宮內妊娠12例，對照組宮內妊娠5例，治療組療效優(yōu)于對照組（P＜0.05）； ②未受孕者術后1年輸卵管通暢情況比較：治療組通暢率55.56%，堵塞率30.56%，對照組通暢率26.00%，，堵塞率50.00%，治療組優(yōu)于對照組（P＜0.05）； ③治療前后的癥狀體征積分情況比較：治療組治療前的總積分平均22.80±7.13，治療后的總積分平均7.77±5.16，對照組治療前的總積分平均22.40±6.94，治療后的總積分平均10.93±7.13，兩組的治療都可以緩解患者的臨床癥狀、體征（P＜0.05），但是兩組治療后的總積分經檢驗無明顯差異（P＞0.05）； ④綜合療效情況比較：治療組30例中治愈12例，顯效6例，有效11例，無效1例，總有效率96.67%，對照組30例中治愈5例，顯效4例，有效13例，無效8例，總有效率73.33%，治療組療效優(yōu)于對照組（P＜0.05）； ⑤病情嚴重程度與宮內妊娠情況比較：16例輕度患者中有9例（56.25%）宮內妊娠，33例中度患者中有7例（21.21%）宮內妊娠，11例重度患者中有1例（9.09%）宮內妊娠，病情程度越輕，宮內妊娠率越高（P＜0.05）； ⑥術后妊娠時間比較：治療組6—12個月內宮內妊娠6例，對照組6—12個月內宮內妊娠1例，治療組優(yōu)于對照組（P＜0.05）。結論：宮腹腔鏡術后結合助孕Ⅱ號方治療輸卵管阻塞性不孕有一定的臨床療效，沒有明顯不良反應，可提高患者宮內妊娠率，防止輸卵管再粘連的發(fā)生。
[Abstract]:Objective: to observe and study the clinical effect of oral Zhiyao No. 2 recipe after hysteroscopy in the treatment of infertile patients with tubal obstruction. Methods: sixty patients who met the screening criteria were randomly divided into treatment group (n = 30) and control group (n = 30). In addition to routine anti-infection treatment after laparoscopic hysteroscopy, the treatment group was treated with oral Zhuyue recipe II. The control group was treated with expectation therapy. Results: 1 comparison of intrauterine pregnancy: there were 12 cases of intrauterine pregnancy in the treatment group and 5 cases in the control group. The curative effect of the treatment group was better than that of the control group (P < 0.05). 2 comparison of tubal patency in patients without pregnancy one year after operation: the patency rate of the treatment group was 55.56%, the blocking rate was 30.56%, the patency rate of the control group was 26.00%, and the blocking rate was 50.00%. The treatment group was superior to the control group (P < 0.05). 3Compared with the scores of symptoms and signs before and after treatment: the average total score was 22.80 鹵7.13 in the treatment group, 7.77 鹵5.16 in the treatment group and 22.40 鹵6.94 in the control group before treatment. The average total score after treatment was 10.93 鹵7.13. Both groups could relieve the clinical symptoms and signs (P < 0.05), but there was no significant difference in the total score between the two groups (P > 0.05). 4 comparison of comprehensive curative effects: in the treatment group, 12 cases were cured, 6 cases were markedly effective, 11 cases were effective, 1 case was ineffective, the total effective rate was 96.67%, 5 cases were cured, 4 cases were markedly effective, 13 cases were effective and 8 cases were ineffective in the control group. The total effective rate was 73.33%. The curative effect of the treatment group was better than that of the control group (P < 0.05). (5) the severity of the disease was compared with that of intrauterine pregnancy: among 16 cases of mild pregnancy, 9 cases (56.25%) were pregnant in uterus, 7 cases (21.21%) in 33 cases were moderate, and there were 9 cases (56.25%) in mild cases and 7 cases (21.21%) in 33 cases. In 11 patients with severe pregnancy, 1 case (9.09%) was pregnant in uterus. The lighter the severity of the disease, the higher the rate of intrauterine pregnancy (P < 0.05). 6 comparison of postoperative pregnancy time: 6 cases of intrauterine pregnancy in the treatment group and 1 case in the control group within 6 times 12 months, the treatment group was better than the control group (P < 0.05). Conclusion: hysteroscopy combined with No. 2 prescription has certain clinical effect in the treatment of tubal obstructive sterility, and there is no obvious adverse reaction, which can improve the rate of intrauterine pregnancy and prevent the recurrence of tubal adhesion.
【學位授予單位】：云南中醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R711.6

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