輔助生殖技術(shù)單卵雙胎相關(guān)因素分析及含單絨毛膜雙胎三胎妊娠減除單絨毛膜雙胎之一的臨床結(jié)局比較
發(fā)布時(shí)間：2019-04-09 19:26
【摘要】：目的探討輔助生殖技術(shù)(ART)治療后行多胎妊娠減胎術(shù)中單卵雙胎(MZT)的發(fā)生和三胎妊娠行單絨毛膜雙胎中一胎減胎術(shù)保留雙胎者的臨床結(jié)局。方法回顧性分析ART治療后行經(jīng)陰道多胎妊娠減胎術(shù)的196例患者的臨床資料,分析比較MZT在不同分組中的發(fā)生情況,同時(shí)比較其中伴單絨毛膜雙胎的三胎妊娠減單絨毛膜雙胎之一者(A組)與不伴單絨毛膜雙胎的三胎妊娠減胎后保留雙胎者(B組)的臨床結(jié)局。結(jié)果 (1)196例患者中MZT所占比率為44.39%(87/196)。MZT占比率在體外受精(IVF)組(0.85%)、卵胞質(zhì)內(nèi)單精子顯微注射(ICSI)組(0.66%)、凍融胚胎移植(FET)組(0.78%)和人工授精(AIH/AID)組(0.16%)間比較差異有統(tǒng)計(jì)學(xué)意義(P=0.001);在輔助孵化(AH)組(1.48%)和無(wú)AH組(0.44%)間比較差異亦有統(tǒng)計(jì)學(xué)意義(P=0.000)。MZT占比率在高齡(≥35歲)和非高齡患者中(P=0.330)及卵裂期胚胎移植組和囊胚期胚胎移植組組間(P=0.950)比較差異無(wú)統(tǒng)計(jì)學(xué)意義。(2)A組和B組患者的平均年齡、平均孕周、新生兒的平均胎齡、平均胎兒出生體質(zhì)量、流產(chǎn)率、早期流產(chǎn)率、晚期流產(chǎn)率、早產(chǎn)率、足月產(chǎn)率、活產(chǎn)率、低出生體質(zhì)量?jī)喊l(fā)生率、新生兒出生缺陷率和妊娠并發(fā)癥率比較,差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 ART行多胎妊娠減胎術(shù)的患者中MZT所占幾率很高,為減少M(fèi)ZT的發(fā)生,盡量選擇單胚胎移植;A組和B組患者臨床結(jié)局無(wú)統(tǒng)計(jì)學(xué)差異,單絨毛膜雙胎中一胎減胎術(shù)可能是安全而可行的。
[Abstract]:Objective to investigate the clinical outcome of single egg twins (MZT) in multiple pregnancy reduction surgery after assisted reproductive technique (ART) treatment and single chorionic twin one fetus reduction in third trimester pregnancy. Methods the clinical data of 196 patients who underwent transvaginal multiple pregnancy reduction after ART treatment were analyzed retrospectively. The incidence of MZT in different groups was analyzed and compared. At the same time, the clinical outcomes of one of the trimester chorionic twins with single chorionic twin pregnancy (group A) and those with unaccompanied chorionic twin trimester (group B) were compared. Results (1) the percentage of MZT in 196 patients was 44.39% (87 / 196). MZT) in the (IVF) group (0.85%), in the intracytoplasmic sperm microinjection group (0.66%), and in the intracytoplasmic sperm microinjection group (0.66%). There was a significant difference between frozen-thawed embryo transfer (FET) group (0.78%) and artificial insemination (AIH/AID) group (0.16%). There was also a significant difference between the assisted hatching (AH) group (1.48%) and the non-AH group (0.44%) (P < 0.05). MZT) and cleavage in the elderly (鈮，
本文編號(hào)：2455470
[Abstract]:Objective to investigate the clinical outcome of single egg twins (MZT) in multiple pregnancy reduction surgery after assisted reproductive technique (ART) treatment and single chorionic twin one fetus reduction in third trimester pregnancy. Methods the clinical data of 196 patients who underwent transvaginal multiple pregnancy reduction after ART treatment were analyzed retrospectively. The incidence of MZT in different groups was analyzed and compared. At the same time, the clinical outcomes of one of the trimester chorionic twins with single chorionic twin pregnancy (group A) and those with unaccompanied chorionic twin trimester (group B) were compared. Results (1) the percentage of MZT in 196 patients was 44.39% (87 / 196). MZT) in the (IVF) group (0.85%), in the intracytoplasmic sperm microinjection group (0.66%), and in the intracytoplasmic sperm microinjection group (0.66%). There was a significant difference between frozen-thawed embryo transfer (FET) group (0.78%) and artificial insemination (AIH/AID) group (0.16%). There was also a significant difference between the assisted hatching (AH) group (1.48%) and the non-AH group (0.44%) (P < 0.05). MZT) and cleavage in the elderly (鈮，
本文編號(hào)：2455470
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