【摘要】：目的了解深圳市觀瀾地區(qū)女性人乳頭瘤病毒(HPV)的感染率、感染亞型和年齡分布特點(diǎn)。方法用分子導(dǎo)流雜交技術(shù)對(duì)就診的16 765名女性行HPV亞型檢測(cè),并對(duì)各個(gè)年齡段的感染情況進(jìn)行分析。結(jié)果 16765例樣本中,檢測(cè)到感染HPV的共4 615例,陽(yáng)性率為27.53%,其中高危型3 434例(20.48%);低危型1 181例(7.04%);在28種HPV亞型感染中,HPV-52亞型感染率最高(3.95%),其次為HPV-16(2.75%),再次為HPV-58(2.32%)。年齡分布以≤20歲感染率最高(36.09%),其次為≥60歲(25.18%),不同年齡段感染率差異有統(tǒng)計(jì)學(xué)意義(P=0.000)。結(jié)論深圳市觀瀾地區(qū)HPV感染率高,以HPV-52、16、58亞型為主;感染年齡段以20歲以下最高,60歲以上次之。需進(jìn)一步對(duì)HPV-52、58亞型進(jìn)行調(diào)查和研究;并加強(qiáng)年輕女性和絕經(jīng)后期HPV感染的監(jiān)測(cè)力度,做好防癌工作。
[Abstract]:Objective to investigate the prevalence, subtype and age distribution of human papillomavirus (HPV) in women in Guantan district of Shenzhen. Methods 16 765 women were tested for HPV subtype by molecular diversion hybridization and the infection status of each age group was analyzed. Results among the 16765 samples, 4615 cases (27.53%) were positive for HPV infection, including 3 434 cases (20.48%) of high risk type, 1 181 cases (7.04%) of low risk type, and 3 434 cases (20.48%) of high risk type, 1 181 cases (7.04%) of low risk type. Among 28 subtypes of HPV infection, the infection rate of HPV-52 subtype was the highest (3.95%), followed by HPV-16 (2.75%) and HPV-58 (2.32%). Age distribution showed the highest infection rate of 鈮，

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