【摘要】：目的建立平湖地區(qū)正常妊娠婦女不同孕期甲狀腺功能參考值范圍,并分析調(diào)查本地區(qū)妊娠合并甲狀腺疾病患病情況。方法對2013年1月-12月在平湖市第二人民醫(yī)院和平湖市婦幼保健院進行妊娠常規(guī)檢查的986例妊娠者和150例同期健康體檢的非妊娠婦女進行研究,其中786例排除甲狀腺疾病高危因素的初產(chǎn)婦作為"標準人群"建立正常參考值范圍。采用化學(xué)發(fā)光免疫法檢測TSH、T3、T4、FT3、FT4、TPOAb、TGAb,根據(jù)建立的妊娠期特異的甲狀腺相關(guān)激素參考值范圍篩查分析平湖地區(qū)妊娠婦女甲狀腺疾病患病情況。結(jié)果檢測的986例孕婦中,甲狀腺功能異常(包括甲狀腺功能亢進癥35例、甲狀腺功能減退癥1例、亞臨床甲狀腺功能減退癥55例)的總患病率為9.2%(91/986),其中以亞臨床甲狀腺功能減退癥最常見,患病率為5.6%,甲狀腺功能亢進癥患病率為3.5%。結(jié)論平湖地區(qū)妊娠婦女合并甲狀腺疾病患病率高,甲狀腺功能亢進癥和亞臨床甲狀腺功能減退癥的患病率明顯高于其他地區(qū),建議妊娠早期篩查甲狀腺功能。
[Abstract]:Objective to establish the reference range of thyroid function in normal pregnant women during different periods of pregnancy in Pinghu area, and to analyze and investigate the incidence of thyroid diseases during pregnancy in this area. Methods from January to December 2013, 986 pregnant women and 150 non-pregnant women who underwent routine pregnancy examinations were studied in the second people's Hospital of Pinghu City and the Maternal and Child Health Care Hospital of Pinghu City. Among them, 786 primipara who excluded high risk factors of thyroid disease were used as "standard population" to establish a normal reference range. The prevalence of thyroid diseases in pregnant women in Pinghu area was analyzed by chemiluminescence immunoassay (TSH,T3,T4,FT3,FT4,TPOAb,TGAb,) according to the reference range of pregnancy-specific thyroid-related hormones. Results among 986 pregnant women, the total prevalence rate of abnormal thyroid function (including 35 cases of hyperthyroidism, 1 case of hypothyroidism and 55 cases of subclinical hypothyroidism) was 9.2% (91 / 986). Among them, subclinical hypothyroidism is the most common, the prevalence rate is 5.6%, and the prevalence rate of hyperthyroidism is 3.5%. Conclusion the prevalence of thyroid diseases in pregnant women in Pinghu area is high, and the prevalence of hyperthyroidism and subclinical hypothyroidism is significantly higher than that in other areas. It is suggested that early pregnancy should be screened for thyroid function.
【作者單位】： 平湖市第二人民醫(yī)院;平湖市婦保所;
【基金】：平湖市科技發(fā)展計劃重點項目(2013-35號)
【分類號】：R714.256
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本文編號：2448312