【摘要】：為了探討高齡女性利用微刺激方案在助孕治療周期中添加重組人生長激素(GH)的作用,本中心以84例高齡女性患者為研究對象(研究組加用GH組52例,對照組未加GH組32例),分析比較GH在微刺激方案助孕治療過程對各項參數(shù)的影響。研究結(jié)果表明,研究組的促性腺激素(Gn)總用量和Gn使用天數(shù)均低于對照組,研究組的HCG日E2值、獲卵數(shù)、MII數(shù)目、2PN數(shù)、卵裂期可利用胚胎數(shù)均高于對照組,其差異均具有顯著性意義(P0.05);研究組的HCG日宮內(nèi)膜厚度、受精率、卵裂率、優(yōu)胚率稍高于對照組,但其差異均無顯著性意義(P0.05)。因此,在微刺激方案中,加用GH對于卵巢低反應的高齡女性患者獲益較大。
[Abstract]:In order to investigate the effect of recombinant human growth hormone (GH) (rhGH) on the treatment cycle of assisted pregnancy in elderly women, 84 elderly women (study group plus GH group, 52 cases) were enrolled in the study. Control group (n = 32) without GH (n = 32), the effects of GH on the parameters in the course of microstimulation therapy were analyzed and compared. The results showed that the total dosage of gonadotropin (Gn) and the duration of use of Gn in the study group were lower than those in the control group, and the E2 value, the number of eggs, the number of MII, the number of 2PN and the number of available embryos at cleavage stage in the study group were higher than those in the control group. The difference was significant (P0.05). The endometrial thickness, fertilization rate, cleavage rate and blastocyst rate of HCG in the study group were slightly higher than those in the control group, but there was no significant difference between the study group and the control group (P0.05). As a result, the use of GH in the microstimulus program benefited older women with low ovarian response.
【作者單位】： 湖南省計劃生育研究所生殖中心;
【分類號】：R714.8
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本文編號：2444475