【摘要】：目的：探討絕經(jīng)前女性子宮內(nèi)膜癌的發(fā)病高危因素、臨床表現(xiàn)及漏誤診情況。 方法：回顧性分析我院2011年10月至2013年10月間收治的經(jīng)組織病理學(xué)確診的123例絕經(jīng)前子宮內(nèi)膜癌及癌前病變患者的臨床資料，分析絕經(jīng)前患者的臨床診斷及漏誤診情況，，并以同期收治的155例絕經(jīng)后患者為對照，對比分析兩組患者的發(fā)病相關(guān)因素及臨床癥狀。 結(jié)果：高血壓、糖尿病、惡性腫瘤史在絕經(jīng)后子宮內(nèi)膜癌患者的發(fā)病中有更為重要的影響，而PCOS、雌激素使用史、惡性腫瘤家族史、未生育等與絕經(jīng)前子宮內(nèi)膜癌關(guān)系更加密切。絕經(jīng)后子宮內(nèi)膜癌患者以不規(guī)則陰道流血，陰道排液為主要表現(xiàn)，臨床表現(xiàn)典型，術(shù)前誤診率為2.58%；而絕經(jīng)前患者以不規(guī)則陰道流血，經(jīng)量增多和（或）經(jīng)期延長為主要表現(xiàn)，臨床表現(xiàn)不典型，漏誤診率高達(dá)13.82%。 結(jié)論：絕經(jīng)前女性子宮內(nèi)膜癌的發(fā)病高危因素不同于絕經(jīng)后女性，且臨床表現(xiàn)不典型，漏誤診率高，臨床上應(yīng)予以重視，以便于早診斷，早治療，改善患者預(yù)后。
[Abstract]:Objective: to investigate the risk factors, clinical manifestations and misdiagnosis of endometrial carcinoma in premenopausal women. Methods: the clinical data of 123 cases of premenopausal endometrial carcinoma and precancerous lesions diagnosed by histopathology from October 2011 to October 2013 were analyzed retrospectively. The clinical diagnosis and misdiagnosis of premenopausal women were analyzed. With 155 postmenopausal patients as control group, the related factors and clinical symptoms of the two groups were analyzed. Results: the history of hypertension, diabetes and malignant tumor was more important in the pathogenesis of postmenopausal endometrial carcinoma, while the history of estrogen use of PCOS, family history of malignant tumor, Infertility is more closely associated with premenopausal endometrial carcinoma. The main manifestations of postmenopausal endometrial carcinoma were irregular vaginal bleeding and vaginal effusion. The clinical manifestations were typical and the misdiagnosis rate was 2.58. The main manifestations of premenopausal patients were irregular vaginal bleeding with increased menstrual volume and / or prolonged menstrual period. The clinical manifestations were atypical and the misdiagnosis rate of leakage was as high as 13.82%. Conclusion: the high risk factors of endometrial carcinoma in premenopausal women are different from those in postmenopausal women, and the clinical manifestations are atypical and the rate of missed misdiagnosis is high. Therefore, attention should be paid to it in clinical practice so as to facilitate early diagnosis, early treatment and improve the prognosis of the patients.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R737.33

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