系統(tǒng)淋巴結(jié)切除在子宮內(nèi)膜癌治療中的臨床意義探討
發(fā)布時間:2019-01-05 14:55
【摘要】:目的:探討子宮內(nèi)膜癌患者在行系統(tǒng)(盆腔加腹主動脈旁)淋巴結(jié)切除的臨床意義,以提高子宮內(nèi)膜癌的療效。方法:收集我院在2007年4月至2012年3月行系統(tǒng)淋巴結(jié)切除,并經(jīng)病理檢查確診為子宮內(nèi)膜癌的患者91例,分析其術中術后情況、腹主動脈旁淋巴結(jié)轉(zhuǎn)移的影響因素及與生存率的關系。結(jié)果:91例患者中29例出現(xiàn)淋巴結(jié)轉(zhuǎn)移,轉(zhuǎn)移率為31.9%,其中盆腔淋巴結(jié)轉(zhuǎn)移20例(22.0%),腹主動脈旁淋巴結(jié)轉(zhuǎn)移23例(25.3%)。發(fā)生術中并發(fā)癥6例(6.6%),術后并發(fā)癥8例(8.8%)。多因素分析顯示,非子宮內(nèi)膜樣癌、低分化(G3)、子宮肌層浸潤深度1/2、盆腔淋巴結(jié)轉(zhuǎn)移是腹主動脈旁淋巴結(jié)轉(zhuǎn)移的獨立危險因素。腹主動脈旁淋巴結(jié)轉(zhuǎn)移患者的累積生存率(36.9%)明顯低于無淋巴結(jié)轉(zhuǎn)移患者累積生存率(91.9%),差異有統(tǒng)計學意義(P0.05)。結(jié)論:系統(tǒng)淋巴結(jié)切除對提高子宮內(nèi)膜癌的療效非常重要,且安全可行。
[Abstract]:Objective: to evaluate the clinical significance of systemic lymphadenectomy in patients with endometrial carcinoma. Methods: from April 2007 to March 2012, 91 patients with endometrial carcinoma were treated with systemic lymphadenectomy and confirmed by pathological examination, and their intraoperative and postoperative conditions were analyzed. Influencing factors of lymph node metastasis and its relationship with survival rate. Results: there were 29 cases of lymph node metastasis in 91 cases (31.9%), including 20 cases (22.0%) of pelvic lymph node metastasis and 23 cases (25.3%) of para-aortic lymph node metastasis. Intraoperative complications occurred in 6 cases (6.6%) and postoperative complications in 8 cases (8.8%). Multivariate analysis showed that non-endometrial carcinoma, low differentiation (G3), myometrium invasion depth of 1 / 2, pelvic lymph node metastasis is an independent risk factor for lymph node metastasis of abdominal aorta. The cumulative survival rate (36.9%) in patients with para-aortic lymph node metastasis was significantly lower than that in patients without lymph node metastasis (91.9%). The difference was statistically significant (P0.05). Conclusion: systematic lymphadenectomy is very important and safe in improving the efficacy of endometrial carcinoma.
【作者單位】: 廣西醫(yī)科大學附屬腫瘤醫(yī)院;
【分類號】:R737.33
[Abstract]:Objective: to evaluate the clinical significance of systemic lymphadenectomy in patients with endometrial carcinoma. Methods: from April 2007 to March 2012, 91 patients with endometrial carcinoma were treated with systemic lymphadenectomy and confirmed by pathological examination, and their intraoperative and postoperative conditions were analyzed. Influencing factors of lymph node metastasis and its relationship with survival rate. Results: there were 29 cases of lymph node metastasis in 91 cases (31.9%), including 20 cases (22.0%) of pelvic lymph node metastasis and 23 cases (25.3%) of para-aortic lymph node metastasis. Intraoperative complications occurred in 6 cases (6.6%) and postoperative complications in 8 cases (8.8%). Multivariate analysis showed that non-endometrial carcinoma, low differentiation (G3), myometrium invasion depth of 1 / 2, pelvic lymph node metastasis is an independent risk factor for lymph node metastasis of abdominal aorta. The cumulative survival rate (36.9%) in patients with para-aortic lymph node metastasis was significantly lower than that in patients without lymph node metastasis (91.9%). The difference was statistically significant (P0.05). Conclusion: systematic lymphadenectomy is very important and safe in improving the efficacy of endometrial carcinoma.
【作者單位】: 廣西醫(yī)科大學附屬腫瘤醫(yī)院;
【分類號】:R737.33
【共引文獻】
相關期刊論文 前10條
1 邱翠華;朱薛艷;;中藥對甲氨蝶呤治療未破裂型異位妊娠療效的影響[J];中醫(yī)藥臨床雜志;2006年02期
2 葉紅娟;;自擬活血解毒湯保留灌腸治療慢性盆腔炎84例[J];中醫(yī)藥臨床雜志;2006年06期
3 張菁;呂秀花;韓云鵬;;益氣固沖湯治療更年期功能失調(diào)性子宮出血46例[J];中醫(yī)藥臨床雜志;2007年01期
4 李,
本文編號:2401916
本文鏈接:http://sikaile.net/yixuelunwen/fuchankeerkelunwen/2401916.html
最近更新
教材專著