【摘要】：目的：回顧性分析應(yīng)用子宮動(dòng)脈栓塞術(shù)(UAE)治療子宮肌瘤的臨床療效。 方法：選擇自2003至2005年于延邊醫(yī)院就診的150例子宮肌瘤患者,對其進(jìn)行子宮動(dòng)脈栓塞術(shù)。檢測術(shù)后副反應(yīng),對比UAE術(shù)后3、6、12、24個(gè)月后患者的臨床癥狀、子宮和肌瘤體積與術(shù)前的變化。 結(jié)果：本組病例術(shù)后均出現(xiàn)不同程度的栓塞后綜合癥,給予對癥治療后癥狀逐漸減輕；術(shù)后6個(gè)月觀察,在50例術(shù)前有明顯經(jīng)量改變的患者中,9例月經(jīng)無明顯改變,41例經(jīng)量明顯減少,經(jīng)期縮短；27例漸進(jìn)性痛經(jīng)患者痛經(jīng)癥狀明顯減輕；3例經(jīng)期縮短患者恢復(fù)正常；14例陰道不規(guī)則流血患者均有明顯好轉(zhuǎn)；術(shù)后12個(gè)月63例輕、中度貧血患者Hb回歸至正常水平；2例重度貧血患者,術(shù)后Hb升高至90g/L以上；盆腔壓迫癥狀患者中85%術(shù)后明顯改善,15%輕度改善；術(shù)后3個(gè)月開始子宮及肌瘤體積分別縮小38.1%和48.3%,6-24個(gè)月兩者均呈進(jìn)行性縮��；10例粘膜下肌瘤6-12個(gè)月后經(jīng)陰道自行排除；術(shù)后6、12、24個(gè)月總有效率分別為90.2%(治愈：10.2%,顯效：67.4%,有效：12.6%)、96.3%(治愈：10.4%,顯效：79.6%,有效：6.3%)、98.3%(治愈：10.9,顯效：85.1%有效：2.3%),顯效率和總有效率與術(shù)后時(shí)間呈正相關(guān)。 結(jié)論：1、應(yīng)用子宮動(dòng)脈栓塞術(shù)治療子宮肌瘤效果顯著,可明顯縮小子宮及肌瘤的體積,緩解臨床癥狀,改善患者生活質(zhì)量,適用于有生育要求的年輕患者和不愿接受手術(shù)治療者。2、經(jīng)子宮動(dòng)脈栓塞術(shù)治療后副反應(yīng)及并發(fā)癥是有限的、可控的。
[Abstract]:Objective: to retrospectively analyze the clinical effect of uterine artery embolization (UAE) in the treatment of uterine leiomyoma. Methods: one hundred and fifty patients with uterine leiomyoma from 2003 to 2005 in Yanbian Hospital were treated with uterine artery embolization. The clinical symptoms, uterine and myoma volumes, and preoperative changes were compared between the patients with UAE and 612,24 months after UAE. Results: postembolization syndrome appeared in all the patients after operation, and the symptoms gradually alleviated after the treatment. 6 months after operation, among 50 patients with significant changes in menstrual volume before operation, 9 cases had no significant change in menstruation, 41 cases had significantly decreased menstrual volume, and 27 cases with progressive dysmenorrhea had reduced dysmenorrhea symptoms. After 12 months, 63 patients with mild and moderate anemia returned to normal level, 2 patients with severe anemia, Hb increased to more than 90g/L after operation, 3 patients with shortened menstrual period returned to normal, 14 patients with irregular vaginal bleeding improved significantly, 63 patients with mild and moderate anemia returned to normal level at 12 months after operation, 2 patients with severe anemia increased to 90g/L after operation. In 85% of the patients with pelvic compression symptoms, the volume of uterus and myoma decreased by 38.1% and 48.3% respectively at 3 months after operation and gradually decreased in 15% and 6 to 24 months after operation, and the volume of uterus and leiomyoma decreased gradually from 3 months to 24 months after operation. 10 cases of submucous myoma were removed by vagina after 6-12 months. The total effective rates were 90.2% in 612 months and 24 months after operation (cure: 10.2um, remarkable effect: 67.4and effective: 12.6%), and 96.3% (cure: 10.4%, remarkable effect: 79.6%, effective: 6.3%). 98.3% (cure: 10.9, effective: 85.1%: 2.3%), the effective rate and total effective rate were positively correlated with the postoperative time. Conclusion: 1. Uterine artery embolization can significantly reduce the volume of uterus and myoma, relieve clinical symptoms and improve the quality of life of patients. Suitable for young patients with fertility requirements and unwilling to undergo surgical treatment. 2. Side effects and complications after transuterine arterial embolization are limited and controllable.
【學(xué)位授予單位】：延邊大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R737.33

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