【摘要】：目的：回顧性分析應用子宮動脈栓塞術(UAE)治療子宮肌瘤的臨床療效。 方法：選擇自2003至2005年于延邊醫(yī)院就診的150例子宮肌瘤患者,對其進行子宮動脈栓塞術。檢測術后副反應,對比UAE術后3、6、12、24個月后患者的臨床癥狀、子宮和肌瘤體積與術前的變化。 結果：本組病例術后均出現(xiàn)不同程度的栓塞后綜合癥,給予對癥治療后癥狀逐漸減輕；術后6個月觀察,在50例術前有明顯經(jīng)量改變的患者中,9例月經(jīng)無明顯改變,41例經(jīng)量明顯減少,經(jīng)期縮短；27例漸進性痛經(jīng)患者痛經(jīng)癥狀明顯減輕；3例經(jīng)期縮短患者恢復正常；14例陰道不規(guī)則流血患者均有明顯好轉；術后12個月63例輕、中度貧血患者Hb回歸至正常水平；2例重度貧血患者,術后Hb升高至90g/L以上；盆腔壓迫癥狀患者中85%術后明顯改善,15%輕度改善；術后3個月開始子宮及肌瘤體積分別縮小38.1%和48.3%,6-24個月兩者均呈進行性縮小；10例粘膜下肌瘤6-12個月后經(jīng)陰道自行排除；術后6、12、24個月總有效率分別為90.2%(治愈：10.2%,顯效：67.4%,有效：12.6%)、96.3%(治愈：10.4%,顯效：79.6%,有效：6.3%)、98.3%(治愈：10.9,顯效：85.1%有效：2.3%),顯效率和總有效率與術后時間呈正相關。 結論：1、應用子宮動脈栓塞術治療子宮肌瘤效果顯著,可明顯縮小子宮及肌瘤的體積,緩解臨床癥狀,改善患者生活質量,適用于有生育要求的年輕患者和不愿接受手術治療者。2、經(jīng)子宮動脈栓塞術治療后副反應及并發(fā)癥是有限的、可控的。
[Abstract]:Objective: to retrospectively analyze the clinical effect of uterine artery embolization (UAE) in the treatment of uterine leiomyoma. Methods: one hundred and fifty patients with uterine leiomyoma from 2003 to 2005 in Yanbian Hospital were treated with uterine artery embolization. The clinical symptoms, uterine and myoma volumes, and preoperative changes were compared between the patients with UAE and 612,24 months after UAE. Results: postembolization syndrome appeared in all the patients after operation, and the symptoms gradually alleviated after the treatment. 6 months after operation, among 50 patients with significant changes in menstrual volume before operation, 9 cases had no significant change in menstruation, 41 cases had significantly decreased menstrual volume, and 27 cases with progressive dysmenorrhea had reduced dysmenorrhea symptoms. After 12 months, 63 patients with mild and moderate anemia returned to normal level, 2 patients with severe anemia, Hb increased to more than 90g/L after operation, 3 patients with shortened menstrual period returned to normal, 14 patients with irregular vaginal bleeding improved significantly, 63 patients with mild and moderate anemia returned to normal level at 12 months after operation, 2 patients with severe anemia increased to 90g/L after operation. In 85% of the patients with pelvic compression symptoms, the volume of uterus and myoma decreased by 38.1% and 48.3% respectively at 3 months after operation and gradually decreased in 15% and 6 to 24 months after operation, and the volume of uterus and leiomyoma decreased gradually from 3 months to 24 months after operation. 10 cases of submucous myoma were removed by vagina after 6-12 months. The total effective rates were 90.2% in 612 months and 24 months after operation (cure: 10.2um, remarkable effect: 67.4and effective: 12.6%), and 96.3% (cure: 10.4%, remarkable effect: 79.6%, effective: 6.3%). 98.3% (cure: 10.9, effective: 85.1%: 2.3%), the effective rate and total effective rate were positively correlated with the postoperative time. Conclusion: 1. Uterine artery embolization can significantly reduce the volume of uterus and myoma, relieve clinical symptoms and improve the quality of life of patients. Suitable for young patients with fertility requirements and unwilling to undergo surgical treatment. 2. Side effects and complications after transuterine arterial embolization are limited and controllable.
【學位授予單位】：延邊大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R737.33

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